Evidence map›Paper›PMID 41510453›Full record

ReviewCureus2025

Effect of Structured Exercise on Blood Pressure in Patients With Rheumatoid Arthritis: A Systematic Review.

Maryam Walizada, Gowtham Siddi, Srirachana Reddy Gumireddy, Mariette Anto, Israa Elkashif, Sindhu Vithayathil, Summayya Anwar

Abstract readReview
In one paragraph

Review in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Maryam WalizadaInternal Medicine, Mary Washington Hospital, Fredericksburg, USA.
Gowtham SiddiInternal Medicine, NRI Academy of Medical Sciences, Guntur, IND.
Srirachana Reddy GumireddyMedicine, Apollo Institute of Medical Sciences and Research, Hyderabad, IND.
Mariette AntoOrthopaedics, King's Mill Hospital, Sutton-in-Ashfield, GBR.
Israa ElkashifPsychiatry, Royal College of Surgeons in Ireland, Dublin, IRL.
Sindhu VithayathilGeneral Medicine, American University of Antigua, Coolidge, ATG.
Summayya AnwarBiosciences, COMSATS University Islamabad, Islamabad, PAK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Rheumatoid arthritis (RA) is a chronic inflammatory autoimmune disease that primarily affects joints and causes mobility problems. RA is associated with high mortality and morbidity as a result of the increased prevalence of cardiovascular disease (CVD) and cardiovascular (CV) risk factors, such as blood pressure (BP), in these patients. Exercise has a beneficial effect on CVD and CV risk factors and improves the overall well-being of RA patients. This systematic review aims to investigate the effect of exercise on CVD and CV risk factors, specifically BP, in RA patients. We searched the relevant literature across databases such as PubMed, PubMed Central, Cochrane Library, ScienceDirect, and Google Scholar. In this study, we included English-language studies with full text and related information on the impact of exercise on CVD in RA patients. The study follows the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) 2020 guidelines. We used the Joanna Briggs Institute (JBI) appraisal method for evaluating non-randomized clinical trials (RCTs), pilot studies, and observational studies, the Assessment of Multiple Systematic Reviews (AMSTAR) checklist for systematic reviews, and the Narrative Review Checklist for the narrative review studies. Eight relevant studies were included in this systematic review. The study shows that different types of exercise, from low to high intensity, have a beneficial effect on CVD and CV risk factors such as BP in RA patients. Exercise improves mortality, morbidity, and overall quality of life in this patient population. The study strongly recommends incorporating physical activity into the management of RA patients.

Indexed as

blood pressurecardiovascular risk factorphysical activityrheumatoid arthritisstructured exercise

Identifiers

PMID41510453
PMCPMC12777848

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.