ReviewCureus2025
Impact of Tympanostomy Tube Placement on Pediatric Developmental Outcomes: A Systematic Review.
Review in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
Abstract
The goal of this study was to systematically review the literature on developmental outcomes following tympanostomy tube insertion (TTI) in pediatric patients with otitis media (OM) and evaluate whether TTI improves language, cognitive, or behavioral functioning compared to conservative management. A systematic review was conducted to identify studies reporting developmental outcomes after TTI in children with OM. Two independent reviewers screened titles, abstracts, and full-text articles using predefined inclusion criteria. Risk of bias was assessed with the Cochrane Risk of Bias 2 tool and MINORS criteria. Of 2,746 studies identified, 13 met inclusion criteria. Study designs included three randomized controlled trials (RCTs), nine prospective cohort studies, and one retrospective study. Ten different developmental measurement instruments (DMIs) were used, targeting cognitive, language, and behavioral domains. Only two RCTs demonstrated statistically significant short-term improvements in developmental outcomes after TTI, particularly in personal-social skills and behavior at nine months post-intervention. However, these gains were not sustained at 18 months. One observational study reported worsening behavioral outcomes after TTI. The remaining studies, including one RCT and several large cohorts, showed no developmental benefit. Heterogeneity in DMIs, inconsistent follow-up duration, and limited demographic and socioeconomic data impeded comparison and synthesis. Evidence supporting developmental improvement following TTI in pediatric OM patients is limited and mixed. While short-term gains are noted in select RCTs, these findings are not consistently replicated. Future research should prioritize standardized outcome measures, better demographic reporting, and clearer stratification by developmental risk to clarify TTI's impact on child development.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.