Evidence map›Paper›PMID 41510391›Full record

ArticleTranslational lung cancer research2025

Patient-reported outcomes of radiofrequency ablation-video-assisted thoracoscopic surgery (VATS) hybrid surgery

Ruifeng Xu, Guochao Zhang, Na Ren, Fanmao Meng, Tiejun Liu, Mengbai Tian, Mufei Sun, Hongrui Wang, Yitong Lu, Xin Liang and 6 more

Abstract read
In one paragraph

Article in Translational lung cancer research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Ruifeng Xu *Department of Thoracic Surgery, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
Guochao Zhang *Department of Thoracic Surgery, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
Na Ren *Department of Thoracic Surgery, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
Fanmao MengDepartment of Thoracic Surgery, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
Tiejun LiuDepartment of Thoracic Surgery, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
Mengbai TianDepartment of Thoracic Surgery, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
Mufei SunDepartment of Thoracic Surgery, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
Hongrui WangDepartment of Thoracic Surgery, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
Yitong LuSchool of Public Health, Capital Medical University, Beijing, China.
Xin LiangDepartment of Medical Management, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
Yu TianSchool of Public Health, Capital Medical University, Beijing, China.
Qi XueDepartment of Thoracic Surgery, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
Xin Sun *Department of Medical Management, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
Yun Che *Department of Thoracic Surgery, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
Shugeng Gao *Department of Thoracic Surgery, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
Liang Zhao *Department of Thoracic Surgery, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Computed tomography-guided radiofrequency ablation combined with video-assisted thoracoscopic surgery (VATS) hybrid surgery (HBD) treats multiple primary lung nodules by simultaneously ablating satellite nodules and resecting the primary lesion. However, its postoperative patient-centered recovery trajectories remain unclear compared to standard VATS. This study aims to illustrate the patient-reported outcomes (PROs) of HBD and VATS, and to investigate whether a hybrid approach can serve as a safe and effective alternative for cases traditionally deemed challenging, thereby potentially expanding the indications for minimally invasive therapy. Methods: A longitudinal cohort study included 183 patients with a primary clinical stage 0/IA non-small cell lung cancer (NSCLC) and at least one additional ipsilateral nodule (118 VATS, 65 HBD) treated at a national cancer center was conducted (April 2024-December 2024). PROs were assessed using the MD Anderson Symptom Inventory-Lung Cancer (MDASI-LC) preoperatively and at 17 timepoints postoperatively (days 1-90). Moderate-to-severe symptoms/functional impairment was defined as scores ≥4/10. Mixed-effects models and Kaplan-Meier analyses evaluated recovery trajectories. Results: A total of 183 patients with stage 0/IA NSCLC (118 VATS, 65 HBD) treated at a national cancer center were selected. Both groups showed similar baseline characteristics except sex distribution (HBD: 83.1% female Conclusions: HBD achieves comparable PRO-based recovery to VATS while preserving lung parenchyma, though with distinct symptom trade-offs.

Indexed as

multiple primary lung cancerpatient-reported outcomes (PROs)radiofrequency ablation (RFA)Video-assisted thoracoscopic

Identifiers

PMID41510391
PMCPMC12775712

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.