ArticleTechnical innovations & patient support in radiation oncology2026
Breast cancer patients with ipsilateral diaphragm paralysis: practical breast radiotherapy using continuous positive airway pressure-assisted breathing to spare normal organs.
Article in Technical innovations & patient support in radiation oncology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Purpose: To describe organs at risk (OARs)-sparing breast cancer (BC) radiotherapy (RT) for patients with ipsilateral (Ipsi-diaphragm) paralysis using continuously positive airway pressure (CPAP) and supine tangential RT-field. Material and method: Breast RT plans with free-breathing (FB) for a patient with right-sided BC (patient1) and another patient with left-sided BC (patient2) showed an elevated Ipsi-diaphragm and displaced portions of liver (patient1) and the heart and intestine (patient2) into supine tangential RT-field. Although both patients denied cardiopulmonary symptoms, their elevated diaphragm, liver, intestine and the heart were unchanged with deep-inspiration breath hold (DIBH) while contralateral diaphragm moved caudally suggesting clinical diagnosis of Ipsi-diaphragm paralysis. Subsequently, patients underwent CT-sim under CPAP to create supine tangential breast RT plan. Result: Compared with FB, CPAP inflated lungs and moved both patients paralyzed diaphragm, liver, heart, and intestine caudally and displaced these OARs away from breast RT-field. The liver volume within right supine tangential RT-fields in patient1 was 163 cc with FB versus 12 cc with CPAP (93 % reduction). The heart and intestine were completely outside the left supine tangential RT-field with CPAP in patient2. For dosimetric comparison, supine tangential RT-fields for breast-only RT were used with prescription of 40 Gy in 15 fractions on each patients' CT-sim with FB and CPAP, respectively. Compared with FB, CPAP reduced liver volume receiving ≥ 30 Gy by 94 % (FB:140 vs CPAP:8 cc) in patient1 and mean dose to the heart by 67 % (FB:2.7 vs CPAP:0.9 Gy) and left anterior descending artery by 84 % (FB:25 vs CPAP:3.9 Gy), maximum dose to the intestine by 90 % (FB:40.6 vs CPAP:4.4 Gy). Conclusion: BC patients with Ipsi-diaphragm paralysis, CPAP provided an effective and practical technique for OARs-sparing breast RT.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.