Evidence map›Paper›PMID 41510297›Full record

ArticleResearch square2025

Comparative transcriptomic analysis of pyrethroid-resistant Anopheles gambiae s.l. from Ghana, reveals concentration-dependent and site-specific patterns of gene expression.

Christopher Mfum Owusu-Asenso, Anisa Abdulai, Isaac Kwame Sraku, Simon Kwaku Attah, Fred Aboagye-Antwi, Yaw Asare Afrane

Abstract readPreprint
In one paragraph

Article in Research square, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors.

Christopher Mfum Owusu-AsensoUniversity of Ghana Medical School.
Anisa AbdulaiUniversity of Ghana Medical School.
Isaac Kwame SrakuUniversity of Ghana Medical School.
Simon Kwaku AttahUniversity of Ghana Medical School.
Fred Aboagye-AntwiUniversity of Ghana.
Yaw Asare AfraneUniversity of Ghana Medical School.

Funding

Regional Centre for Vector Borne Diseases in West Africa (RCVBD)D43TW011513 · FIC · UNIVERSITY OF GHANA · PI YAW ASARE AFRANE, Guiyun Yan · 2021 to 2026
$1.5M
Invasive Anopheles stephensi in Ghana: Sampling Tools and Vector Population DynamicsR03AI186018 · NIAID · COLLEGE OF HEALTH SCIENCES, UNIVERSITY OF GHANA · PI AFRANE, YAW ASARE · 2024 to 2025
$108k
FIC NIH HHS D43 TW011513NIAID NIH HHS R03 AI186018
6 · The paper itself

Abstract

The role of detoxification enzymes in pyrethroid resistance intensity among malaria vectors remains a critical area of research. This study evaluated the role of detoxifying enzymes in driving resistance intensity in

Indexed as

Anopheles gambiae s.l.concentration-dependent gene expressionkdr mutationsmetabolic gene expressionPyrethroid resistance intensitysite-specific gene expression

Identifiers

PMID41510297
PMCPMC12776479

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.