ArticleResearch square2025
Impact of Gestational Maternal SARS-CoV-2 Infection on Neonatal Inflammatory Biomarkers.
Article in Research square, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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11 authors.
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Abstract
Background: Since the beginning of the pandemic, millions of pregnant women have been exposed to SARS-CoV-2, raising concerns about maternal and fetal sequelae. Yet, the impact of SARS-CoV-2 on the child's immune response remains largely unexplored. Herein, we leverage 833 mother-infant dyads from a New York City-based pregnancy cohort, to explore prospective associations between maternal gestational SARS-CoV-2 infection and inflammatory biomarkers in newborns. Of the mothers, 100 were infected with SARS-CoV-2 during pregnancy, as confirmed through self-report, antibody and/or PCR test results. We obtained 92 inflammatory biomarker levels in neonatal dried blood spots (DBS) using the Olink Results: Higher levels of 22 inflammatory biomarkers ( Conclusion: Our results indicate that maternal SARS-CoV-2 infection during pregnancy impacts inflammatory biomarkers in newborns, with the timing of infection playing a critical role in shaping these immune profiles. Thus, this study underscores the need for further research and long-term follow-up to assess any potential future health consequences for the child.
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