Evidence map›Paper›PMID 41510167›Full record

ReviewTheranostics2026

Lead radionuclides for theranostic applications in nuclear medicine: from atom to bedside.

Yani Berckmans, Janke Kleynhans, Sara Van Mechelen, Karolien Goffin, Kristof Baete, Michel Koole, An Coosemans, Thomas Elias Cocolios, Christophe M Deroose, Yann Seimbille and 1 more

Abstract readReview
In one paragraph

Review in Theranostics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Yani BerckmansKU Leuven, Department of Oncology, Laboratory for Tumor Immunology and Immunotherapy, Leuven Cancer Institute, Leuven, 3000, Belgium.
Janke KleynhansKU Leuven, Department of Pharmaceutical and Pharmacological Sciences, Laboratory for Radiopharmaceutical Research, Leuven, 3000, Belgium.
Sara Van MechelenKU Leuven, Department of Oncology, Laboratory for Tumor Immunology and Immunotherapy, Leuven Cancer Institute, Leuven, 3000, Belgium.
Karolien GoffinKU Leuven, Department of Imaging and Pathology, Nuclear Medicine and Molecular Imaging, Leuven, 3000, Belgium.
Kristof BaeteKU Leuven, Department of Imaging and Pathology, Nuclear Medicine and Molecular Imaging, Leuven, 3000, Belgium.
Michel KooleKU Leuven, Department of Imaging and Pathology, Nuclear Medicine and Molecular Imaging, Leuven, 3000, Belgium.
An CoosemansKU Leuven, Department of Oncology, Laboratory for Tumor Immunology and Immunotherapy, Leuven Cancer Institute, Leuven, 3000, Belgium.
Thomas Elias CocoliosKU Leuven, Department of Physics and Astronomy, Institute for Nuclear and Radiation Physics, Leuven, 3001, Belgium.
Christophe M DerooseKU Leuven, Department of Imaging and Pathology, Nuclear Medicine and Molecular Imaging, Leuven, 3000, Belgium.
Yann SeimbilleDepartment of Radiology and Nuclear Medicine, Erasmus MC, 3015 CN Rotterdam, The Netherlands.
Frederik CleerenKU Leuven, Department of Pharmaceutical and Pharmacological Sciences, Laboratory for Radiopharmaceutical Research, Leuven, 3000, Belgium.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Lead-212 has emerged as a promising radionuclide for targeted alpha therapy (TAT), positioning itself at the forefront of next-generation cancer treatments. What sets lead-212 apart is its unique decay profile: while it is a beta emitter, it mainly serves as an

Indexed as

Lead RadioisotopesNeoplasmsNuclear MedicineRadioisotopesRadiopharmaceuticalsTheranostic NanomedicineAnimalsHalf-LifeHumansTomography, Emission-Computed, Single-PhotonLead-212Lead RadioisotopesRadioisotopesRadiopharmaceuticalslead-203lead-212radionuclide therapy (RNT)single-photon emission tomography (SPECT)targeted alpha therapy (TAT)targeted radionuclide therapy (TRT)

Identifiers

PMID41510167
PMCPMC12775822

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.