Evidence map›Paper›PMID 41510159›Full record

ArticleTheranostics2026

Quantitative dynamic granzyme B PET imaging to characterize novel combination immunotherapy response in preclinical glioblastoma models.

Carlos A Gallegos, Yun Lu, Patrick N Song, Rodrigo Queiroz, Ugur Akca, Sharmila Sridhar, Jennifer L Bartels, Yujun Zhang, Li Li, Jason M Warram and 4 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Theranostics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Carlos A GallegosDepartment of Biomedical Engineering, University of Alabama at Birmingham, Birmingham, AL.
Yun LuDepartment of Radiology, University of Alabama at Birmingham, Birmingham, AL.
Patrick N SongDepartment of Radiology, University of Alabama at Birmingham, Birmingham, AL.
Rodrigo QueirozDepartment of Radiology, University of Alabama at Birmingham, Birmingham, AL.
Ugur AkcaDepartment of Biomedical Engineering, University of Alabama at Birmingham, Birmingham, AL.
Sharmila SridharDepartment of Radiology, University of Alabama at Birmingham, Birmingham, AL.
Jennifer L BartelsDepartment of Radiology, University of Alabama at Birmingham, Birmingham, AL.
Yujun ZhangDepartment of Radiology, University of Alabama at Birmingham, Birmingham, AL.
Li LiDepartment of Neurosurgery, University of Alabama at Birmingham, Birmingham, AL.
Jason M WarramDepartment of Otolaryngology, University of Alabama at Birmingham, Birmingham, AL.
Suzanne E LapiDepartment of Radiology, University of Alabama at Birmingham, Birmingham, AL.
Benjamin M LarimerDepartment of Radiology, University of Alabama at Birmingham, Birmingham, AL.
James M MarkertDepartment of Neurosurgery, University of Alabama at Birmingham, Birmingham, AL.
Anna G SoraceDepartment of Biomedical Engineering, University of Alabama at Birmingham, Birmingham, AL.

Funding

XRAY CRYSTALLOGRAPHYP30CA013148 · NCI · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI Omer Jamy · 1985 to 2026
$165.9M
Utilization of Immuno-PET to detect response and guide novel oHSV-based therapy for gliomaR01CA279143 · NCI · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI JAMES M MARKERT, Anna C Sorace · 2023 to 2026
$2.3M
Major upgrade for UAB Bruker BioSpec preclinical 9.4T MRIS10OD028498 · OD · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI SORACE, ANNA C · 2020 to 2020
$601k
NCI NIH HHS P30 CA013148NCI NIH HHS R01 CA279143NIH HHS S10 OD028498
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Brain NeoplasmsGlioblastomaGranzymesImmunotherapyPositron-Emission TomographyAnimalsCell Line, TumorCopper RadioisotopesDisease Models, AnimalFemaleHumansMagnetic Resonance ImagingMiceTumor MicroenvironmentCopper RadioisotopesGranzymescompartment modelingdynamic PETglioblastomaimmunotherapyoHSV

Identifiers

PMID41510159
PMCPMC12775653

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.