Evidence map›Paper›PMID 41510129›Full record

ArticleObesity science & practice2026

Associations of Fitness, Fatness Indices and Fit-Fat Index Variants With Cardiovascular and All-Cause Mortality in Men.

Nzechukwu M Isiozor, Setor K Kunutsor, Sudhir Kurl, Kai Savonen, Jussi Kauhanen, Jari A Laukkanen

Abstract read
In one paragraph

Article in Obesity science & practice, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Nzechukwu M IsiozorInstitute of Clinical Medicine School of Medicine University of Eastern Finland Kuopio Finland.
Setor K KunutsorSection of Cardiology Department of Internal Medicine Max Rady College of Medicine Rady Faculty of Health Sciences University of Manitoba Winnipeg Manitoba Canada.
Sudhir KurlBrain Research Unit School of Medicine University of Eastern Finland Kuopio Finland.
Kai SavonenKuopio Research Institute of Exercise Medicine Kuopio Finland.
Jussi KauhanenInstitute of Public Health and Clinical Nutrition University of Eastern Finland Kuopio Finland.
Jari A LaukkanenInstitute of Clinical Medicine School of Medicine University of Eastern Finland Kuopio Finland.ORCID https://orcid.org/0000-0002-3738-1586

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Fit-Fat Index (FFI), defined as the ratio of cardiorespiratory fitness (CRF) to waist-to-height ratio (WHtR), combines measures of fitness and fatness, and may offer a more accurate assessment of cardiometabolic risk than either component alone. The prospective associations of CRF, fatness indices, and mortality were examined. Methods: CRF and fatness indices (body mass index [BMI], waist-to-hip ratio [WHR], and WHtR) were assessed in 1089 men aged 42-61 years. FFI variants (FFI Results: Over a median follow-up of 31.2 years, 288 CVD deaths and 695 all-cause deaths were recorded. After multivariable adjustment, the HR (95% CI) for CVD death per 1 SD increase was 0.81 (0.70-0.93) for CRF, 1.09 (0.96-1.23) for BMI, 1.13 (1.02-1.25) for WHR, 1.13 (0.99-1.30) for WHtR, 0.82 (0.71-0.95) for FFI Conclusions: Combining aerobic fitness and fatness into FFI measures may provide better risk stratification than either aerobic fitness or fatness alone.

Indexed as

cardiorespiratory fitnesscardiovascular diseasecohort studyfatnessfit–fat‐indexmortality

Identifiers

PMID41510129
PMCPMC12774866

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.