Evidence map›Paper›PMID 41510035›Full record

ArticleIranian journal of microbiology2025

Sulfonamide resistance, virulence traits, and in-silico target interactions among clinical isolates in Setif, Algeria (2021-2023).

Anfal Kara, Imane Krache, Naouel Boussoualim, Roufaida Bourouche, Naouel Hamani, Malek Nour Kheloufi, Yacine Benguerba

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Article in Iranian journal of microbiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Anfal KaraDepartment of Microbiology, Faculty of Natural and Life Sciences, Ferhat Abbas Sétif 1 University, Sétif, Algeria.
Imane KracheDepartment of Biochemistry, Faculty of Natural and Life Sciences, Ferhat Abbas Sétif 1 University, Sétif, Algeria.
Naouel BoussoualimDepartment of Microbiology, Faculty of Natural and Life Sciences, Ferhat Abbas Sétif 1 University, Sétif, Algeria.
Roufaida BouroucheDepartment of Microbiology, Faculty of Natural and Life Sciences, Ferhat Abbas Sétif 1 University, Sétif, Algeria.
Naouel HamaniDepartment of Microbiology, Faculty of Natural and Life Sciences, Ferhat Abbas Sétif 1 University, Sétif, Algeria.
Malek Nour KheloufiDepartment of Microbiology, Faculty of Natural and Life Sciences, Ferhat Abbas Sétif 1 University, Sétif, Algeria.
Yacine BenguerbaDepartment of Processes Engineering, Ferhat Abbas Sétif 1 Universit, Sétif, Algeria.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background and Objectives: Antibiotic-resistant bacteria are a growing global health concern, particularly in developing regions. Sulfonamides, once widely used, now face increasing resistance. This study assessed the prevalence, resistance profiles, and virulences traites of sulfonamide-resistant strains in Sétif, Algeria (2021-2023). Materials and Methods: A total of 215 clinical isolates were collected from patients aged 1 day to 96 years (mean 42.7). Most were community-acquired (77.2%), with urinary tract infections predominating (49.3% in women, 32.1% in men). Identification and susceptibility testing followed standard microbiological and Kirby-Bauer methods. Virulence factors (biofilm, hemolysin, protease, lecithinase, and lipase) were examined. Molecular docking compared sulfamethoxazole and trimethoprim binding to their enzymatic targets. Results: Conclusion: The high prevalence of multidrug-resistant bacteria, especially

Indexed as

Anti-bacterial agentsDrug resistanceMolecular docking simulationSulfonamidesVirulence factors

Identifiers

PMID41510035
PMCPMC12777792

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