Evidence map›Paper›PMID 41509966›Full record

ArticleInternational journal of clinical pediatric dentistry2025

Evaluation of Chitosan (Axiostat®) as a Pulpotomy Agent in Primary Molars: An

Nidhish Krishna, Kavita Rai, R Manju, Nikita Lolayekar

Abstract read
In one paragraph

Article in International journal of clinical pediatric dentistry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Nidhish KrishnaDepartment of Pediatric and Preventive Dentistry, AB Shetty Memorial Institute of Dental Sciences, NITTE (Deemed to be University), Mangaluru, Karnataka, India.
Kavita RaiDepartment of Pediatric and Preventive Dentistry, AB Shetty Memorial Institute of Dental Sciences, NITTE (Deemed to be University), Mangaluru, Karnataka, India.
R ManjuDepartment of Pediatric and Preventive Dentistry, AB Shetty Memorial Institute of Dental Sciences, NITTE (Deemed to be University), Mangaluru, Karnataka, India.
Nikita LolayekarDepartment of Pediatric and Preventive Dentistry, AB Shetty Memorial Institute of Dental Sciences, NITTE (Deemed to be University), Mangaluru, Karnataka, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: In primary teeth, pulpotomy is a well-established intervention for managing cariously exposed coronal pulp, with formocresol long considered the gold-standard medicament. Recent research focuses on wound-healing phenomena and the use of regenerative materials like chitosan owing to its functional versatility and unique characteristics. Aim: To assess the clinical and radiographic outcomes of using chitosan as a pulpotomy agent in primary molars. Materials and methods: Children aged 4-9 years, free from systemic illnesses and in need of pulpotomy, were selected. About 50 teeth were assigned to two groups: group I (chitosan) and group II (formocresol), and all treated teeth received stainless-steel crowns. Clinical and radiographic parameters were assessed at 1, 3, and 6 months posttreatment. The Chi-squared test was applied to compare the parameters and analyze the differences between the groups at the various time intervals. Results: Group I (chitosan) demonstrated a clinical and radiographic success rate of 95.6%, while group II (formocresol) achieved 100%. The variation between the groups was not statistically significant. Conclusion: The study indicated that chitosan (Axiostat®) can be considered a reliable pulpotomy agent in primary dentition and an effective substitute for formocresol. How to cite this article: Krishna N, Rai K, Manju R,

Indexed as

AxiostatChitosanFormocresolPrimary teethPulpotomy

Identifiers

PMID41509966
PMCPMC12776850

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.