Evidence map›Paper›PMID 41509922›Full record

ArticleiScience2026

Multifunctional carboxymethyl cellulose-based hydrogels with zwitterionic and silver nanowire components for wound management.

Kit-Leong Cheong, Te Pan, Suresh Veeraperumal, Franck Quero, Gowsika Jaikumar, Timo Kikas, Malairaj Sathuvan, Karsoon Tan, Saiyi Zhong, Udayakumar Veerabagu

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In one paragraph

Article in iScience, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Kit-Leong CheongCollege of Food Science and Technology, Guangdong Ocean University, Zhanjiang 524088, China.
Te PanCollege of Food Science and Technology, Guangdong Ocean University, Zhanjiang 524088, China.
Suresh VeeraperumalDepartment of Biology, College of Science, Shantou University, Shantou, Guangdong, China.
Franck QueroLaboratorio de Nanocelulosa y Biomateriales, Departamento de Ingeniería Química, Biotecnología y Materiales, Facultad de Ciencias Físicas y Matemáticas, Universidad de Chile, Santiago 8370456, Chile.
Gowsika JaikumarDepartment of Chemistry, Pachaiyappa's College, University of Madras, Chennai 600030, India.
Timo KikasChair of Biosystems Engineering, Institute of Forestry and Engineering, Estonian University of Life Sciences, Kreutzwaldi 56, 51014 Tartu, Estonia.
Malairaj SathuvanCenter for Global Health Research, Saveetha Medical College and Hospital, Saveetha Institute of Medical and Technical Sciences, Kancheepuram, Tamil Nadu, India.
Karsoon TanGuangxi Key Laboratory of Beibu Gulf Biodiversity Conservation, Beibu Gulf University, Qinzhou, Guangxi, China.
Saiyi ZhongCollege of Food Science and Technology, Guangdong Ocean University, Zhanjiang 524088, China.
Udayakumar VeerabaguLaboratorio de Nanocelulosa y Biomateriales, Departamento de Ingeniería Química, Biotecnología y Materiales, Facultad de Ciencias Físicas y Matemáticas, Universidad de Chile, Santiago 8370456, Chile.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Chronic wounds represent a major global health burden, while conventional dressings often fail to meet the complex requirements of chronic wound management, including infection control, moisture balance, and tissue regeneration. In this study, two multifunctional zwitterionic hydrogels-vinylpyridine carboxybetaine/sulfobetaine/silver nanowire/carboxymethyl cellulose (VCS/Ag/CMC) and acrylamide carboxybetaine/sulfobetaine/silver nanowire/carboxymethyl cellulose (ACS/Ag/CMC) - were synthesized. Structural analyses confirmed the successful incorporation of aromatic or aliphatic zwitterionic components and uniform distribution of silver nanowires within the CMC-based hydrogel networks. Both hydrogels exhibited favorable mechanical strength, high swelling capacity, controlled degradability, and sustained silver release, providing a balanced profile for chronic wound applications.

Indexed as

BiomaterialsBiotechnologyCell biologyMaterials in biotechnology

Identifiers

PMID41509922
PMCPMC12775929

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.