Evidence map›Paper›PMID 41509852›Full record

ReviewJournal of spine surgery (Hong Kong)2025

Nerve injuries in cervical spine surgery via anterior approach: a comprehensive review.

Sazid Hasan, Neal Farmer, Isaac Arefi, Mackenzie Hagood, Pranav Gadangi, Haytham Alqasmi, Muhammad Waheed, Abdul-Lateef Shafau, Yasser Abusabha, Ehab Saleh and 2 more

Abstract readReview
In one paragraph

Review in Journal of spine surgery (Hong Kong), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Sazid HasanDepartment of Orthopaedic Surgery, University of Toledo, Toledo, OH, USA.
Neal FarmerDepartment of Orthopaedic Surgery, University of Toledo, Toledo, OH, USA.
Isaac ArefiDepartment of Orthopaedic Surgery, University of Toledo, Toledo, OH, USA.
Mackenzie HagoodDepartment of Orthopaedic Surgery, University of Toledo, Toledo, OH, USA.
Pranav GadangiDepartment of Orthopaedic Surgery, University of Toledo, Toledo, OH, USA.
Haytham AlqasmiDepartment of Orthopaedic Surgery, Detroit Medical Center, Detroit, MI, USA.
Muhammad WaheedDepartment of Orthopaedic Surgery, Detroit Medical Center, Detroit, MI, USA.
Abdul-Lateef ShafauDepartment of Orthopaedic Surgery, Detroit Medical Center, Detroit, MI, USA.
Yasser AbusabhaDepartment of Orthopaedic Surgery, University of Toledo, Toledo, OH, USA.
Ehab SalehDepartment of Orthopaedic Surgery, Beaumont Hospital Royal Oak, Royal Oak, MI, USA.
Jad KhalilDepartment of Orthopaedic Surgery, Beaumont Hospital Royal Oak, Royal Oak, MI, USA.
Hossein ElgafyDepartment of Orthopaedic Surgery, University of Toledo, Toledo, OH, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Anterior cervical spine surgery is widely performed to manage degenerative, traumatic, and compressive spinal conditions. Despite its effectiveness, iatrogenic nerve injuries remain a significant concern due to the complex anatomy of the cervical region. This review offers a focused narrative on nerve injuries associated with anterior cervical approaches, including recurrent and superior laryngeal nerve palsy, C5 nerve root palsy, and hypoglossal nerve injury. Less common complications such as Parsonage-Turner syndrome (PTS), C8-T1 radiculopathy, and Horner's syndrome are also addressed. Each injury is discussed in terms of anatomical relevance, incidence, clinical features, diagnosis, and strategies for prevention and management. A structured review of PubMed-indexed literature from the past 25 years was conducted to ensure the inclusion of current evidence. Risk factors such as multilevel surgery, revision procedures, and excessive retraction are highlighted. While many nerve injuries are self-limited, a subset may result in long-term deficits, reinforcing the need for meticulous surgical planning and intraoperative care. By increasing awareness of these complications, this review aims to inform surgical technique and reduce morbidity in anterior cervical spine surgery. This review emphasizes not only the incidence and anatomical relevance of these complications, but also underscores the importance of preventive measures such as careful retraction, intraoperative neuromonitoring, and preoperative planning. By synthesizing data across multiple studies and including rare complications such as Horner's syndrome and PTS, this review provides a practical reference for surgeons aiming to reduce morbidity. Ultimately, the goal is to improve surgical safety and patient quality of life through heightened awareness and refinement of technique.

Indexed as

anterior approachinjury preventionnerve injuriesPostoperative complications

Identifiers

PMID41509852
PMCPMC12775630

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.