Evidence map›Paper›PMID 41509849›Full record

ArticleJournal of spine surgery (Hong Kong)2025

Long cervical fusions: are multiple segmental plates less likely to fail than a single long plate?

Gregory Mundis, Hani Malone, Gautham Prabhakar, Fernando Rios, Austin Williams, Darryl D'Lima, Stephen Stephan, Robert Eastlack

Abstract read
In one paragraph

Article in Journal of spine surgery (Hong Kong), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors.

Gregory MundisDepartment of Orthopaedic Surgery, Scripps Clinic, La Jolla, CA, USA.
Hani MaloneDepartment of Orthopaedic Surgery, Scripps Clinic, La Jolla, CA, USA.
Gautham PrabhakarDepartment of Orthopaedic Surgery, Scripps Clinic, La Jolla, CA, USA.
Fernando RiosChristus Muguerza Hospital Alta Especialidad, Chihuahua, Mexico.
Austin WilliamsShiley Center for Orthopaedic Research and Education (SCORE) at Scripps, San Diego, CA, USA.
Darryl D'LimaShiley Center for Orthopaedic Research and Education (SCORE) at Scripps, San Diego, CA, USA.
Stephen StephanDepartment of Orthopaedic Surgery, Scripps Clinic, La Jolla, CA, USA.
Robert EastlackDepartment of Orthopaedic Surgery, Scripps Clinic, La Jolla, CA, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Anterior cervical discectomy and fusion (ACDF) is widely performed for cervical pathology, yet multilevel anterior constructs are associated with higher rates of dysphagia, pseudoarthrosis, and mechanical failure-particularly at the caudal segment. These complications may arise from stress concentration and load transfer through long anterior cervical plates. Segmentally separated fixation, utilizing multiple short plates rather than a single long plate, may reduce these risks by limiting exposure, shortening operative time, and distributing mechanical loads more evenly. The purpose of this study was to compare the biomechanical behavior of multilevel ACDF constructs stabilized with multiple segmental plates versus a single long plate. Methods: Twelve fresh-frozen human cadaveric cervical spines (C4-C7) underwent ACDF using either a single long plate or multiple segmental plates. Bone quality was quantified via C7 trabecular Hounsfield units on computed tomography (CT), and specimens were randomized by density. Identical constructs were also tested in polyurethane foam cervical models to minimize biological variability. Specimens were mounted to multiaxial test platforms and subjected to fatigue cycling under flexion-extension, lateral bending, and axial rotation. Construct stiffness was recorded at baseline and after 1,500 cycles in each motion plane. Stiffness loss was analyzed with one-way analysis of variance (ANOVA) and normalized to bone density. Results: Initial construct stiffness did not differ between groups (P=0.86). After cyclic loading, multiple segmental plates demonstrated significantly greater stiffness retention in axial rotation (51%±10% Conclusions: Segmentally separated anterior fixation for multilevel ACDF preserves rotational stiffness at the caudal segment more effectively than long single-plate constructs in controlled models. This suggests a potential mechanical advantage that may translate to reduced stress concentration and lower failure risk in multilevel anterior cervical reconstructions. Further

Indexed as

anterior cervical discectomy and fusion (ACDF)cervicalplatingSegmental

Identifiers

PMID41509849
PMCPMC12775606

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.