Evidence map›Paper›PMID 41509762›Full record

ArticleJournal of orthopaedic case reports2025

The Use of Botulinum Toxin in Pre-pubic Aponeurotic Complex Injuries: A Case Series.

Andrea Bisciotti, Gian Nicola Bisciotti, Alessio Auci, Alessandro Bisciotti, Gabriella Cassaghi, Federica Parra Maria

Abstract read
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Article in Journal of orthopaedic case reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

6 authors.

Andrea BisciottiDepartment of Knee Surgery, IRCCS Humanitas Research Hospital, Rozzano, Italy.
Gian Nicola BisciottiKinemove Rehabilitation Centers, Pontremoli, Italy.
Alessio AuciDepartment of Radiology, New Apuano Hospital USL Toscana Nord-Ovest, Massa, Italy.
Alessandro BisciottiKinemove Rehabilitation Centers, Pontremoli, Italy.
Gabriella CassaghiKinemove Rehabilitation Centers, Pontremoli, Italy.
Federica Parra MariaKinemove Rehabilitation Centers, Pontremoli, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Injuries of the pre-pubic aponeurotic complex (PPAC) are a significant cause of groin pain syndrome. These injuries tend to have limited self-healing capacity because the injured area is kept apart by opposing forces exerted by the rectus abdominis (RA) and adductor longus muscles. Recently, botulinum toxin type A (BTX-A) has been successfully used in a case report describing a patient with PPAC injuries. This study aims to evaluate the efficacy of BTX-A in a series of patients with PPAC injuries. Materials and Methods: Ten male athletic subjects with PPAC injuries underwent infiltrative therapy with BTX-A at the level of the RA and adductor longus, followed by an 8-week rehabilitation program. Results: Ultrasound assessment performed after the rehabilitation program showed that 9 subjects (90%) achieved complete restitutio ad integrum of the PPAC injury area, while 1 subject (10%) exhibited partial repair. At 12 months of follow-up, 9 patients (90%) returned to sports activity, 8 (80%) at the same level, and 1 (10%) at a lower level, but not due to residual pain. No adverse effects were recorded. Conclusion: BTX-A infiltrative therapy appears to be a safe, effective, and promising treatment for PPAC injuries, enabling a quick return to sporting activity.

Indexed as

Botulinum toxingroin pain syndromepre-pubic aponeurotic complex

Identifiers

PMID41509762
PMCPMC12778920

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.