Evidence map›Paper›PMID 41509630›Full record

ArticleFASEB bioAdvances2026

Impact of a GABA-Producing

Kristina Hill, Alexandra LaFollette, Trevor O Kirby, Soledad Negrete, Dani Babcock, Kari Felton, Hannah Kohl, Kavita Sharma, Andrea Castillo, Jean-Baptiste Roullet and 2 more

Abstract read
In one paragraph

Article in FASEB bioAdvances, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Impact of a GABA-ProducingFASEB bioAdvances · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Kristina HillBiomolecular Sciences Graduate Program Boise State University Boise Idaho USA.
Alexandra LaFolletteDepartment of Biological Sciences Boise State University Boise Idaho USA.
Trevor O KirbyAG1, Research, Nutrition, and Innovation Carson City Nevada USA.
Soledad NegreteDepartment of Biological Sciences Boise State University Boise Idaho USA.
Dani BabcockDepartment of Biological Sciences Boise State University Boise Idaho USA.
Kari FeltonDepartment of Biological Sciences Boise State University Boise Idaho USA.
Hannah KohlDepartment of Biology Eastern Washington University Cheney Washington USA.
Kavita SharmaDepartment of Biology Eastern Washington University Cheney Washington USA.
Andrea CastilloDepartment of Biomedical and Pharmaceutical Sciences Idaho State University Pocatello Idaho USA.
Jean-Baptiste RoulletDepartment of Pharmacotherapy, College of Pharmacy and Pharmaceutical Sciences Washington State University Spokane Washington USA.
K Michael GibsonDepartment of Pharmacotherapy, College of Pharmacy and Pharmaceutical Sciences Washington State University Spokane Washington USA.
Javier Ochoa-RepárazBiomolecular Sciences Graduate Program Boise State University Boise Idaho USA.ORCID https://orcid.org/0000-0001-9610-3175

Funding

Women's health: interplay of maternal diet and key demographics on neurological health in the rural frontier and remote WestP20GM103408 · NIGMS · UNIVERSITY OF IDAHO · PI Scott A Minnich · 2012 to 2026
$59.8M
VPS35 D620N inhibits autophagy through disrupted hyaluronic acid-CD44 signalingP20GM109095 · NIGMS · BOISE STATE UNIVERSITY · PI OCHOA-REPARAZ, JAVIER · 2014 to 2023
$22.7M
Supplement for Google cloud build-outR24GM137786 · NIGMS · UNIV OF ARKANSAS FOR MED SCIS · PI Alan Tackett · 2020 to 2026
$15.4M
Optimizing Deep Brain Stimulation for Parkinson's Disease.P20GM148321 · NIGMS · BOISE STATE UNIVERSITY · PI Javier Ochoa-Reparaz · 2023 to 2026
$10.2M
Targeting the GABA-modulator microbiota against the progression of CNS inflammatory demyelinationR15NS107743 · NINDS · EASTERN WASHINGTON UNIVERSITY · PI OCHOA-REPARAZ, JAVIER, ROULLET, JEAN-BAPTISTE O · 2019 to 2019
$419k
NIGMS NIH HHS P20 GM103408NIGMS NIH HHS P20 GM109095NIGMS NIH HHS P20 GM148321NIGMS NIH HHS R24 GM137786NINDS NIH HHS R15 NS107743
6 · The paper itself

Abstract

Gut microbes are key regulators of immune homeostasis. Their composition fluctuates over time and between individuals and is also influenced by disease. We and others have reported changes in gut bacterial composition following induction of experimental autoimmune encephalomyelitis (EAE), a well-established model for multiple sclerosis (MS). Specifically, we observed reductions in the abundance of bacteria capable of producing gamma-aminobutyric acid (GABA). Because GABA regulates immune cell function, we genetically engineered a

Indexed as

EAEGABALactococcus lactismicrobiotamycobiotaproteomics

Identifiers

PMID41509630
PMCPMC12777695

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.