Evidence map›Paper›PMID 41509573›Full record

ArticleCureus2026

Nicotine Pouch Patterns of Use in a 10-Week Prospective Study.

Lindsay Reese, Elliott H McDowell, Brian Erkkila, Tryggve Ljung

Abstract read
In one paragraph

Article in Cureus, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Lindsay ReeseLife Sciences, Philip Morris International (PMI) R&D, Philip Morris Products S.A., Neuchâtel, CHE.
Elliott H McDowellRegulatory, Philip Morris International (PMI) US Corporate Services, Stamford, USA.
Brian ErkkilaScientific Engagement, Philip Morris International (PMI) US Corporate Services, Stamford, USA.
Tryggve LjungLife Sciences, Philip Morris International (PMI) R&D, Philip Morris Products S.A., Neuchâtel, CHE.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundNicotine pouch (NP) product use has increased in the US, but limited data are available on how NPs are used and if they affect the use of other tobacco and/or nicotine products (TNPs), specifically transition away from more harmful TNPs such as cigarettes.

methodsThis prospective, observational study gathered information on daily use patterns of combustible and non-combustible TNPs (cigarettes, cigars, pipe tobacco, hookah, e-cigarettes, oral smokeless tobacco (ST)) and reasons for use among current adult NP users (n=346, ≥18 years old during the 2017-2018 study period) recruited with canister stickers in the 11 states where

resultsThe proportion of participants who used NP-Z and smoked cigarettes at least one day a week at baseline decreased from 15.9% (12.0-19.8%) to 8.1% (5.2-11.0%) over the study period. Nearly half of them stopped smoking by week 10 (8.1% (5.2-11.0%) to 4.9% (2.6-7.2%)). Among those who used NP-Z and moist snuff, use of the latter declined from 15.0% (11.2-18.8%) to 7.5% (4.7-10.3%). Overall, 24.0% (19.5-28.5%) of participants who used NP-Z and other TNPs at baseline reported exclusive NP-Z use by the end of the 10-week study.

conclusionPatterns of use among early NP-Z adopters indicate that NPs can be acceptable replacements for other TNPs, particularly cigarettes and oral ST.

Indexed as

nicotine pouchespost-market surveillanceswitching behaviortobacco harm reductiontobacco use behavior

Identifiers

PMID41509573
PMCPMC12777431

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.