Evidence map›Paper›PMID 41509539›Full record

ArticleJournal of exercise science and fitness2026

The impact of tangeretin combined with whey protein supplementation on body composition and hormonal profiles in elite sprinters: A double-blind RCT.

Zhi Cao, Zheng Zhang, Meng Liu

Abstract read
In one paragraph

Article in Journal of exercise science and fitness, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Zhi CaoSchool of Athletic Performance, Shanghai University of Sport, Shanghai, China.
Zheng ZhangResearch Center for Integration of Exercise Promotion and Pharmaceutical Care, China Pharmaceutical University, Nanjing, China.
Meng LiuChongqing University, Chongqing, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: This study explored the combined effects of tangeretin and whey protein on serum testosterone and cortisol in competitive athletes. Methods: In a double-blind,controlled trial, 24 elite sprinters were divided into two groups: an experimental group (EXP, n = 12) taking tangeretin (200 mg) and whey protein (19.8 g) daily, and a control group (CTRL, n = 12) taking only whey protein (19.8 g) over four weeks. Weekly and post-intervention tests measured serum testosterone, cortisol, superoxide dismutase (SOD) activity, and adrenocorticotropic hormone (ACTH) levels, along with pre- and post-intervention anthropometric assessments. Results: After intervention, a significant Time × Group interaction was observed for fat-free mass (FFM), which increased significantly in the EXP but not in the CTRL, with a greater percentage increase in EXP (2.3 % vs. 1.1 %, p = 0.018). Similar interactions were found for fat mass and body fat percentage, which decreased significantly in EXP. For biochemical indicators, no significant Group × Time interactions were found. However, a significant main effect of time was identified for serum testosterone and ACTH, indicating comparable temporal changes in both groups. No significant time or interaction effects were observed for cortisol, T/C ratio and SOD. Conclusion: Four weeks of combined whey protein and tangeretin supplementation significantly improved body composition in elite sprinters, whereas it did not significantly alter systemic hormonal profiles or antioxidant activity compared to whey protein alone.

Indexed as

Body compositionSerum cortisolSerum testosteroneSprinterTangeretin

Identifiers

PMID41509539
PMCPMC12775955

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.