Evidence map›Paper›PMID 41509440›Full record

ArticlebioRxiv : the preprint server for biology2025

Sleep-Wake Transitions Are Impaired in the

Ryan K Tisdale, Yu Sun, Stephanie R Miller, Stephanie M Lee, Sunmee Park, Jia Shin, Giancarlo Allocca, Jorge J Palop, Thomas S Kilduff

Abstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Ryan K TisdaleCenter for Neuroscience, Biosciences Division, SRI International, Menlo Park, CA, 94025 USA.
Yu SunCenter for Neuroscience, Biosciences Division, SRI International, Menlo Park, CA, 94025 USA.
Stephanie R MillerGladstone Institute of Neurological Disease, San Francisco, CA, 94158 USA.
Stephanie M LeeCenter for Neuroscience, Biosciences Division, SRI International, Menlo Park, CA, 94025 USA.
Sunmee ParkCenter for Neuroscience, Biosciences Division, SRI International, Menlo Park, CA, 94025 USA.
Jia ShinGladstone Institute of Neurological Disease, San Francisco, CA, 94158 USA.
Giancarlo AlloccaFlorey Department of Neuroscience and Mental Health, University of Melbourne, Parkville, Australia.
Jorge J PalopGladstone Institute of Neurological Disease, San Francisco, CA, 94158 USA.
Thomas S KilduffCenter for Neuroscience, Biosciences Division, SRI International, Menlo Park, CA, 94025 USA.ORCID 0000-0002-6823-0094

Funding

NEURAL GENE EXPRESSION IN SLEEP DEPRIVATION AND RECOVERYR01HL059658 · NHLBI · STANFORD UNIVERSITY · PI KILDUFF, THOMAS S · 1997 to 2023
$8.7M
Nociceptin, NOPR and Sleep/Wake ControlR01NS136808 · NINDS · SRI INTERNATIONAL · PI Thomas S Kilduff · 2024 to 2026
$2.7M
Machine Learning Approaches for Behavioral Phenotyping of Humanized Knock-in Models of Alzheimer's DiseaseK01AG083732 · NIA · J. DAVID GLADSTONE INSTITUTES · PI MILLER, STEPHANIE REGINA · 2023 to 2025
$452k
NHLBI NIH HHS R01 HL059658NIA NIH HHS K01 AG083732NINDS NIH HHS R01 NS136808
6 · The paper itself

Abstract

Poor sleep quality and reduced sleep duration are associated with Alzheimer's disease (AD)-related β-amyloid (Aβ) pathologies. We conducted two studies of sleep/wake, activity and body temperature in

Indexed as

ActivityAmyloid Precursor ProteinBody temperatureMultiple Sleep Latency TestNeurodegenerationNREM sleepREM sleepSleep homeostasisβ-amyloid

Identifiers

PMID41509440
PMCPMC12776331

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.