ArticlebioRxiv : the preprint server for biology2025
Rescuing Neurodevelopmental Deficits in AMPA Receptor Gain-of-Function Mutant.
Chih-Ming Chen, Yu-Min Huang, Chih-Ching Chung, Richard C Johnson, Cheng-Ya Tsai, Yu-Han Chen, Han L Tan, Fu-Yun Hsiao, Richard L Huganir, Shu-Ling Chiu
Abstract readPreprint
In one paragraphArticle in bioRxiv : the preprint server for biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registryThe trial behind it
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3 · Its place in the literatureWho cites it
0 citing papers in PubMed.
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4 · The recordCorrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
5 · Who and what moneyAuthors and funding
10 authors.
Chih-Ming ChenInstitute of Cellular and Organismic Biology and Neuroscience Program of Academia Sinica (NPAS), Academia Sinica; Taipei 115, Taiwan.
Yu-Min HuangInstitute of Cellular and Organismic Biology and Neuroscience Program of Academia Sinica (NPAS), Academia Sinica; Taipei 115, Taiwan.
Chih-Ching ChungInstitute of Cellular and Organismic Biology and Neuroscience Program of Academia Sinica (NPAS), Academia Sinica; Taipei 115, Taiwan.
Richard C JohnsonSolomon H. Snyder Department of Neuroscience and Kavli Neuroscience Discovery Institute, Johns Hopkins University School of Medicine; Baltimore, MD 21205, United States.
Cheng-Ya TsaiInstitute of Cellular and Organismic Biology and Neuroscience Program of Academia Sinica (NPAS), Academia Sinica; Taipei 115, Taiwan.
Yu-Han ChenInstitute of Cellular and Organismic Biology and Neuroscience Program of Academia Sinica (NPAS), Academia Sinica; Taipei 115, Taiwan.
Han L TanSolomon H. Snyder Department of Neuroscience and Kavli Neuroscience Discovery Institute, Johns Hopkins University School of Medicine; Baltimore, MD 21205, United States.
Fu-Yun HsiaoInstitute of Cellular and Organismic Biology and Neuroscience Program of Academia Sinica (NPAS), Academia Sinica; Taipei 115, Taiwan.
Richard L HuganirSolomon H. Snyder Department of Neuroscience and Kavli Neuroscience Discovery Institute, Johns Hopkins University School of Medicine; Baltimore, MD 21205, United States.ORCID 0000-0001-9783-5183 Shu-Ling ChiuInstitute of Cellular and Organismic Biology and Neuroscience Program of Academia Sinica (NPAS), Academia Sinica; Taipei 115, Taiwan.ORCID 0000-0003-4429-7830 Funding
The Dynamic AMPA Receptor Interactome During Plasticity and LearningR37NS036715 · NINDS · JOHNS HOPKINS UNIVERSITY · PI Richard L Huganir · 2022 to 2026
$3.2MNINDS NIH HHS R37 NS036715
6 · The paper itselfAbstract
AMPA receptors (AMPARs) mediate fast excitatory synaptic transmission and are essential for neuronal development and brain function. We investigated the role of a recurrent variant in the AMPAR GluA1 subunit
Identifiers
PMID41509361
PMCPMC12776281
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