Evidence map›Paper›PMID 41509354›Full record

ArticlebioRxiv : the preprint server for biology2025

CRISPR screening reveals genetic regulators associated with the evolution of eye degeneration.

Devin Shennard, Charlotte Mulliniks, Estephany Ferrufino, Aubrey Manning, Stefan Choy, Rianna Ambosie, Shiyanth Thevasagayampillai, Brooke Pileggi, Lane Zimmermann, Chenxiao Shen and 8 more

Abstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors.

Devin ShennardDepartment of Biological Sciences, Lehigh University, Bethlehem, PA.
Charlotte MulliniksDepartment of Biological Sciences, Lehigh University, Bethlehem, PA.
Estephany FerrufinoDepartment of Biological Sciences, Lehigh University, Bethlehem, PA.
Aubrey ManningDepartment of Biological Sciences, Lehigh University, Bethlehem, PA.
Stefan ChoyDepartment of Biological Sciences, Lehigh University, Bethlehem, PA.
Rianna AmbosieDepartment of Biological Sciences, Lehigh University, Bethlehem, PA.
Shiyanth ThevasagayampillaiDepartment of Biology and Biochemistry, University of Houston, Houston, TX.
Brooke PileggiDepartment of Biological Sciences, Lehigh University, Bethlehem, PA.
Lane ZimmermannDepartment of Biological Sciences, Lehigh University, Bethlehem, PA.
Chenxiao ShenDepartment of Biological Sciences, Lehigh University, Bethlehem, PA.
Alli KimmelDepartment of Biological Sciences, Lehigh University, Bethlehem, PA.
Renee MapaDepartment of Biological Sciences, Lehigh University, Bethlehem, PA.
Preethi H GunaratneDepartment of Biology and Biochemistry, University of Houston, Houston, TX.
Erik R DuboueWilkes Honors College, Florida Atlantic University, Jupiter, FL.
Wynn K MeyerDepartment of Biological Sciences, Lehigh University, Bethlehem, PA.
Beau AlwardDepartment of Integrative Biology and Physiology, University of California, Los Angeles, Los Angeles, CA.
Suzanne McGaughEcology, Evolution, and Behavior, 140 Gortner Lab, 1479 Gortner Ave, University of Minnesota, Saint Paul, MN 55108, USA.
Johanna E KowalkoDepartment of Biological Sciences, Lehigh University, Bethlehem, PA.

Funding

Evolutionary approaches to identify genetic architecture regulating aggressionR35GM138345 · NIGMS · LEHIGH UNIVERSITY · PI KOWALKO, JOHANNA E. · 2020 to 2024
$2.0M
NIGMS NIH HHS R35 GM138345
6 · The paper itself

Abstract

Determining the genetic factors contributing to trait evolution is critical for understanding how and why traits evolve; however, establishing which genes underlie the evolution of complex traits remains challenging. The freshwater fish

Identifiers

PMID41509354
PMCPMC12776404

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.