Evidence map›Paper›PMID 41509308›Full record

ArticlebioRxiv : the preprint server for biology2025

Impact of Absent in Melanoma 2 (AIM2) on Antigen-Specific CD4+ T cell Activation and Homeostasis.

Dakota M Reinartz, Chloe Sairs, Wang Gong, Yu Leo Lei, Michael S Kuhns, Justin E Wilson

Abstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Dakota M ReinartzDepartment of Immunobiology, University of Arizona, Tucson, AZ.ORCID 0000-0002-7221-4329
Chloe SairsDepartment of Immunobiology, University of Arizona, Tucson, AZ.
Wang GongDepartment of Cancer Biology, University of Texas M.D. Anderson Cancer Center, Houston, TX.
Yu Leo LeiDepartment of Cancer Biology, University of Texas M.D. Anderson Cancer Center, Houston, TX.
Michael S KuhnsDepartment of Immunobiology, University of Arizona, Tucson, AZ.ORCID 0000-0002-0403-6313
Justin E WilsonDepartment of Immunobiology, University of Arizona, Tucson, AZ.ORCID 0000-0002-2803-3280

Funding

VITAMIN AP30CA023074 · NCI · UNIVERSITY OF ARIZONA · PI Bonnie LaFleur · 1985 to 2026
$110.2M
Restoring the Immunogenicity of Head and Neck CancerR01DE026728 · NIDCR · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI Yu Leo Lei, James J. Moon · 2018 to 2026
$4.3M
Probing the mechanistic basis for T cell fate decisions (R01)R01AI101053 · NIAID · UNIVERSITY OF ARIZONA · PI KUHNS, MICHAEL S · 2012 to 2021
$3.5M
Advancing On-Slide and Optical Biopsy Tools to Detect High-Risk Oral PremalignancyU01DE033330 · NIDCR · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI Steven Bennett Chinn, Yu Leo Lei · 2023 to 2026
$2.7M
Evolution-guided analysis of extracellular and intracellular mechanisms driving T cell activationR01AI179713 · NIAID · UNIVERSITY OF ARIZONA · PI Michael S Kuhns, Koenraad Van Doorslaer · 2024 to 2026
$2.0M
Infection and Inflammation as Drivers of Aging (IIDA) Predoctoral Training ProgramT32AG058503 · NIA · UNIVERSITY OF ARIZONA · PI Kristian Paul Doyle, JANKO Z. NIKOLICH · 2019 to 2026
$1.9M
Impact of AIM2 on Intestinal Stem Cell Differentiation During InflammationR01DK141491 · NIDDK · UNIVERSITY OF ARIZONA · PI Justin Ethan Wilson · 2025 to 2026
$1.1M
Contribution of Innate Immune Sensing on Head and Neck Squamous Cell Carcinoma (HNSCC)F31DE032263 · NIDCR · UNIVERSITY OF ARIZONA · PI REINARTZ, DAKOTA MICHAEL · 2022 to 2023
$81k
NCI NIH HHS P30 CA023074NIAID NIH HHS R01 AI101053NIAID NIH HHS R01 AI179713NIA NIH HHS T32 AG058503NIDCR NIH HHS F31 DE032263NIDCR NIH HHS R01 DE026728NIDCR NIH HHS U01 DE033330NIDDK NIH HHS R01 DK141491
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Identifiers

PMID41509308
PMCPMC12776336

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.