Evidence map›Paper›PMID 41509236›Full record

ArticlebioRxiv : the preprint server for biology2025

The

Patricia Irizarry-Barreto, Jennifer Smolyn, Victoria Brown, Bhagavathi Ramamurthy, Martha C Soto

Abstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

  • Updated by
    The2026
5 · Who and what money

Authors and funding

5 authors.

Patricia Irizarry-BarretoDepartment of Pathology and Laboratory Medicine, RWJMS.ORCID 0000-0003-1629-6347
Jennifer SmolynDepartment of Pathology and Laboratory Medicine, RWJMS.
Victoria BrownDepartment of Pathology and Laboratory Medicine, RWJMS.
Bhagavathi RamamurthyDepartment of Physician Assistant Studies and Practice, SHP, Rutgers University.
Martha C SotoDepartment of Pathology and Laboratory Medicine, RWJMS.ORCID 0000-0002-6571-3349

Funding

IRACDA at Rutgers: INSPIRE Postdoctoral Training ProgramK12GM093854 · NIGMS · UNIV OF MED/DENT NJ-R W JOHNSON MED SCH · PI Detlev Boison, Gary A. Brewer · 2010 to 2026
$14.7M
Enhancing and expanding the CGC Strain CollectionP40OD010440 · OD · UNIVERSITY OF MINNESOTA · PI Aric L Daul, Ann E. Rougvie · 2012 to 2026
$7.5M
Molecular mechanisms initiating cell migrations in Caonorhabditis elegansR01GM081670 · NIGMS · UNIV OF MED/DENT NJ-R W JOHNSON MED SCH · PI SOTO, MARTHA C. · 2009 to 2023
$4.3M
Laser Spinning Disc Confocal System for live-cell and live-organism microscopyS10OD010572 · OD · UNIV OF MED/DENT NJ-R W JOHNSON MED SCH · PI SOTO, MARTHA C. · 2012 to 2012
$386k
NIGMS NIH HHS K12 GM093854NIGMS NIH HHS R01 GM081670NIH HHS P40 OD010440NIH HHS S10 OD010572
6 · The paper itself

Abstract

Epithelial polarity requires polarized distribution of the apical adhesion complex that connects cells through the Cadherin transmembrane protein. Cadherin is intimately linked to the actin cytoskeleton through alpha catenin, which directly binds F-actin to set up the apical actin belt. Branched actin is formed when the Arp2/3 complex is activated by Nucleation Promoting Factors.

Identifiers

PMID41509236
PMCPMC12776458

What OpenQuestion holds

Textmetadata
LicenceCC BY-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.