Evidence map›Paper›PMID 41509197›Full record

ArticleFood science & nutrition2026

Dihydroquercetin Attenuates Silica-Induced Pulmonary Fibrosis by Modulating the Gut Microbiota and the Serum Metabolites in Mice.

Zunqiong Ke, Lishu Lin, Yunhong Long, Wenhui Zhang, Jianmin Guo, Leyong Yuan

Abstract read
In one paragraph

Article in Food science & nutrition, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Zunqiong KeDepartment of Clinical Laboratory The Second People's Hospital of Futian District Shenzhen Shenzhen China.
Lishu LinDepartment of Clinical Laboratory The Second People's Hospital of Futian District Shenzhen Shenzhen China.
Yunhong LongDepartment of Clinical Laboratory The Second People's Hospital of Futian District Shenzhen Shenzhen China.
Wenhui ZhangDepartment of Clinical Laboratory The Second People's Hospital of Futian District Shenzhen Shenzhen China.
Jianmin GuoDepartment of Health Management, The Eighth Affiliated Hospital Sun Yat-Sen University Shenzhen China.
Leyong YuanDepartment of Clinical Laboratory The Second People's Hospital of Futian District Shenzhen Shenzhen China.ORCID https://orcid.org/0000-0001-9245-1500

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Dihydroquercetin (DHQ), a crucial dihydroflavone found in nature, demonstrates notable antioxidant, anti-inflammatory, and antifibrotic effects. Nevertheless, the impact on the gut microbiome and metabolites associated with silicosis remains unclear. Hence, the objective of this research was to examine how DHQ impacts silicosis and the associated mechanisms through analyzing gut microbiota with 16S rRNA sequencing and conducting serum metabolomic analysis. The findings of our study showed that administering DHQ significantly attenuated the level of inflammation and fibrosis in the lung tissues of C57BL/6 mice exposed to silica. Furthermore, DHQ clearly raised the amount of Muribaculaceae, while diminishing the amount of

Indexed as

correlation analysisdihydroquercetingut microbiotapulmonary fibrosisserum metabolites

Identifiers

PMID41509197
PMCPMC12778433

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.