ArticleClinical pediatric endocrinology : case reports and clinical investigations : official journal of the Japanese Society for Pediatric Endocrinology2026
The serum oxytocin correlated with serum leptin and body mass index in Japanese adolescents.
Article in Clinical pediatric endocrinology : case reports and clinical investigations : official journal of the Japanese Society for Pediatric Endocrinology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Oxytocin (OXT), a hypothalamic neuropeptide traditionally associated with reproduction and social bonding, has recently garnered attention for its role in regulating appetite and energy metabolism. To evaluate serum OXT levels and their association with adipokines in obese adolescents and those with type 2 diabetes mellitus (T2DM) compared to healthy controls. In this cross-sectional study, we included 27 participants-9 obese (median age [interquartile range] 10.0 [8.7-13.0] yr; men/women 3/6), 7 T2DM (16.0 [13.0-17.0] yr; 6/1), and 11 controls (10.8 [7.5-15.9] yr; 9/2). Serum OXT and adipokine levels were measured via the enzyme-linked immunosorbent assay. OXT levels were higher in patients with T2DM (130 [110-380] pg/mL) than in controls (85 [60-95] pg/mL;
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