ArticleJournal of oral microbiology2026
Alteration in tongue coating microbiota across different stages of hepatitis B virus-related chronic liver disease.
Article in Journal of oral microbiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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14 authors.
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Abstract
Background: Hepatitis B virus-related chronic liver disease (HBV-CLD), chronic hepatitis B (CHB), liver cirrhosis (LC), and hepatocellular carcinoma (HCC) patients' tongue coating microbiota dysbiosis has not yet been clearly defined. Objectives: We aimed to reveal shifts in the bacterial composition of tongue coating microbiota during the progression of HBV-CLD in three different phases. Design: We examined tongue coating microbiota of 16 healthy individuals and 81 patients with HBV-CLD, including 25 with CHB, 27 with LC, and 29 with HCC, using 16S rRNA gene sequencing technique. Results: The bacterial richness in tongue coating was higher in patients with HBV-CLD (all Conclusions: Our investigation revealed tongue coating microbiota dysbiosis in patients with HBV-CLD, which may offer unique diagnostic possibilities and provide microbial biomarkers for monitoring disease progression.
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