ArticleJournal of oral microbiology2026
The dynamic elimination effect of local adjuvant therapy on the periodontal microbiota.
Article in Journal of oral microbiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Redefining microbial clearance and ecological recovery in periodontal microbiome studies.Journal of oral microbiology · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
11 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Implementing local adjunctive therapy during scaling and root planing has become increasingly crucial for optimizing the therapeutic efficacy of periodontitis and reshaping the periodontal microecological environment. Objective: This study aimed to reveal the additional clearance effect of local adjunctive therapy on the microbiota of periodontitis. Design: An autologous randomized controlled trial included 25 periodontitis patients. After scaling and root planing, one oral side randomly received laser or minocycline, the other as control. Three hundred and seventy-six subgingival samples were collected at nine time points within 1 month for integrated analysis of microbiota and clinical indicators. Results: Compared with laser adjunctive therapy, minocycline hydrochloride adjunctive therapy showed no difference in pathogen clearance rate within 6 h, but significant differences emerged in days 1, 3 and 7 ( Conclusions: Minocycline hydrochloride local adjunctive therapy outperforms semiconductor laser local adjunctive therapy in terms of eliminating periodontitis core bacteria, improving the microbial community structure, and enhancing clinical indicators.
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Registered trials
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