ArticleReproductive medicine and biology
Incidence of Retained Products of Conception Following Hormone Replacement Versus Natural Cycles in Frozen Embryo Transfer.
Article in Reproductive medicine and biology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
1 citing paper in PubMed.
- Incidence of Retained Products of Conception Following Hormone Replacement Versus Natural Cycles in Frozen Embryo Transfer.Reproductive medicine and biologyArticle
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Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Purpose: This study examined whether the incidence of retained products of conception (RPOC) differs between hormone replacement cycles (HRC) and natural ovulation cycles (NC) in frozen-thawed embryo transfer (FET) pregnancies. Methods: We retrospectively analyzed 425 clinical pregnancies following FET at a single center from 2017 to 2021. Pregnancies were classified as HRC ( Results: RPOC occurred in 14/425 pregnancies (3.3%), with 11/204 (5.4%) in HRC and 3/221 (1.4%) in NC. The Cochran-Mantel-Haenszel odds ratio was 4.47 (95% confidence interval [CI] 1.29-16.39), and the adjusted Firth odds ratio was 3.92 (95% CI 1.18-12.96). Among RPOC cases, 5 were managed conservatively, 8 required uterine evacuation, and 1 required uterine artery embolization; histopathological confirmation was obtained in 7 cases. No significant associations were observed with embryo-transfer-related procedures. Conclusion: HRC was associated with a higher RPOC incidence than NC. These exploratory findings suggest potential protocol-related differences in placental separation and warrant validation in larger, prospective multicenter studies.
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Registered trials
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