Evidence map›Paper›PMID 41508972›Full record

ArticleCurrent HIV research2026

Serological and Molecular Prevalence of HCMV, HCV, HBV and

Farzaneh Dehghani-Dehej, Mohammad Hossein Razizadeh, Khadijeh Khanaliha, Seyed Jalal Kiani, Tahereh Donyavi, Nikoo Emtiazi, Sara Chavoshpour, Sogol Jamshidi, Farah Bokharaei-Salim

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Article in Current HIV research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Farzaneh Dehghani-DehejDepartment of Virology, School of Medicine, Iran University of Medical Sciences, Tehran, Iran.
Mohammad Hossein RazizadehDepartment of Genetics, Genomics and Cancer Sciences, University of Leicester, Leicester, United Kingdom.
Khadijeh KhanalihaResearch Center of Pediatric Infectious Diseases, Institute of Immunology and Infectious Diseases, Iran University of Medical Sciences, Tehran, Iran.ORCID 0000-0003-3264-8496
Seyed Jalal KianiDepartment of Virology, School of Medicine, Iran University of Medical Sciences, Tehran, Iran.
Tahereh DonyaviDepartment of Medical Biotechnology, Faculty of Allied Medicine, Iran University of Medical Sciences, Tehran, Iran.
Nikoo EmtiaziDepartment of Pathology, Iran University of Medical Sciences, Tehran, Iran.
Sara ChavoshpourDepartment of Virology, Faculty of Medical Sciences, Tarbiat Modares University, Tehran, Iran.
Sogol JamshidiDepartment of Virology, Faculty of Medical Sciences, Tarbiat Modares University, Tehran, Iran.
Farah Bokharaei-SalimDepartment of Virology, School of Medicine, Iran University of Medical Sciences, Tehran, Iran.ORCID 0000-0002-5367-0847

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionCo-infections with human cytomegalovirus (HCMV), hepatitis B virus (HBV), hepatitis C virus (HCV), and Toxoplasma gondii (T. gondii) pose clinical challenges in human immunodeficiency virus-1 (HIV-1)-infected individuals by complicating disease progression and management. This study aimed to investigate the serological and molecular prevalence of HCMV, HBV, HCV, and T. gondii co-infections among treatment-naive HIV-infected individuals.

methodsA cross-sectional study was conducted from March 2022 to August 2024 on 203 treatment- naive HIV-1-infected individuals. Plasma samples were analyzed using ELISA for serological markers and real-time PCR for molecular detection. Statistical analyses were performed to assess demographic and clinical variables associated with co-infections.

resultsAmong the 203 participants, the prevalence of anti-HCV antibodies, HBsAg, HCMV IgM, and T. gondii IgM was 9.9%, 2.5%, 1.5%, and 0.5%, respectively. Molecular detection confirmed active HBV, HCV, and HCMV infections in 40%, 60%, and 66.7% of seropositive individuals, respectively, while T. gondii DNA was undetected. HCV genotyping revealed subtype 1a as the most common (50%), followed by 3a (37.5%) and 1b (12.5%). DISCUSSION: The findings indicate a moderate prevalence of HBV and HCV co-infections and a low prevalence of HCMV and T. gondii co-infections in treatment-naive HIV patients.

conclusionThese results highlight the need for targeted public health interventions, including vaccination and screening strategies, to reduce the risk of co-infections in HIV-infected individuals.

Indexed as

CoinfectionCytomegalovirus InfectionsHepatitis BHepatitis CHIV InfectionsToxoplasmosisAdultCross-Sectional StudiesCytomegalovirusFemaleHepacivirusHepatitis B virusHumansMaleMiddle AgedPrevalencehepatitis B virushepatitis C virushuman cytomegalovirusHuman immunodeficiency virus 1public health interventionsToxoplasma gondii

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.