Evidence map›Paper›PMID 41508956›Full record

ArticleMolecular medicine reports2026

[Retracted] TIPE‑2 suppresses growth and aggressiveness of hepatocellular carcinoma cells through downregulation of the phosphoinositide 3‑kinase/AKT signaling pathway.

Lin Wang, Chen Chen, Shuzhi Feng, Jianli Tian

Abstract readRetraction Notice
In one paragraph

Article in Molecular medicine reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors.

Lin WangDepartment of Geriatrics, Tianjin Medical University General Hospital, Tianjin Geriatrics Institute, Tianjin 300052, P.R. China.
Chen ChenDepartment of Geriatrics, Tianjin Medical University General Hospital, Tianjin Geriatrics Institute, Tianjin 300052, P.R. China.
Shuzhi FengDepartment of Geriatrics, Tianjin Medical University General Hospital, Tianjin Geriatrics Institute, Tianjin 300052, P.R. China.
Jianli TianDepartment of Geriatrics, Tianjin Medical University General Hospital, Tianjin Geriatrics Institute, Tianjin 300052, P.R. China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Following the publication of the above paper, it was drawn to the Editor's attention by a concerned reader that certain of the immunofluorescence data shown in Fig. 1F, cell viability assay data in Fig. 2F, the 'Control' data for the tissue images relating to apoptotic experiments in Fig. 5B and the 'CHOP/TIPE‑2' histological data in Fig. 5E were strikingly similar to data in articles written by different authors at different research institutes that had either already been published previously in other journals, or which were submitted for publication at around the same time (in the interim, one of those articles has been retracted). In addition, western blot data featured in Fig. 2 were rather similar to data appearing in Fig. 3, suggesting that the same data may have been included in these figures to show the results from purportedly differently performed experiments. The Editorial Office were able to draw the same conclusions as the reader based upon an independent analysis of the contentious data in question. Therefore, owing to the fact that some of these data had already been published prior to its submission to

Indexed as

apoptosishepatocellular carcinoma cellsmetastasisphosphoinositide 3‑kinase/protein kinase Btumor necrosis factor‑α‑induced protein‑8 like‑2

Identifiers

PMID41508956
PMCPMC12794589

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.