Evidence map›Paper›PMID 41508834›Full record

ArticleActa dermato-venereologica2026

Incidence and Mortality of Mycosis Fungoides and Sezary Syndrome: A Nationwide Registry Study in Finland.

Anu Partanen, Marjaana Häyrinen, Milla E L Kuusisto, Anna Anttalainen, Liisa Ukkola-Vuoti, Iiro Toppila, Hanne Kuitunen, Tatu Miettinen, Aino Rönkä, Outi Kuittinen

Abstract read
In one paragraph

Article in Acta dermato-venereologica, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Anu Partanen *Department of Medicine, Kuopio University Hospital, Kuopio, Finland. anu.partanen@pshyvinvointialue.fi.ORCID 0000-0002-5634-2582
Marjaana Häyrinen *Oncology, Faculty of Health Medicine, School of Medicine, Institute of Clinical Medicine, University of Eastern Finland, Kuopio, Finland.
Milla E L KuusistoMedical Research Center, Oulu University Hospital, Oulu, Finland; Biomedicine and Internal Medicine Research Unit, University of Oulu, Oulu, Finland; Department of Internal Medicine, Länsi-Pohja Central Hospital, The Wellbeing County of Lapland, Kemi, Finland.ORCID 0000-0002-4435-4199
Anna AnttalainenMedaffcon Oy, Espoo, Finland.ORCID 0000-0002-4041-8044
Liisa Ukkola-VuotiMedaffcon Oy, Espoo, Finland.ORCID 0000-0002-0770-361X
Iiro ToppilaMedaffcon Oy, Espoo, Finland.
Hanne KuitunenCancer Center, Oulu University Hospital, Oulu, Finland.
Tatu MiettinenTakeda Oy, Helsinki, Finland.
Aino RönkäOncology, Faculty of Health Medicine, School of Medicine, Institute of Clinical Medicine, University of Eastern Finland, Kuopio, Finland; Cancer Centre, Kuopio University Hospital, Kuopio, Finland.ORCID 0000-0001-6007-3648
Outi KuittinenOncology, Faculty of Health Medicine, School of Medicine, Institute of Clinical Medicine, University of Eastern Finland, Kuopio, Finland; Cancer Centre, Kuopio University Hospital, Kuopio, Finland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study investigated the incidence, mortality, and causes of death in Finnish patients with mycosis fungoides (MF) or Sezary syndrome (SS). The study population consisted of 450 patients with MF and 23 with SS and their 1:1 matched controls. Data were collected from nationwide Finnish healthcare registries. The average incidence of MF was 0.38 and of SS 0.02 per 100,000 persons in 2007-2019 and was highest among older adults. Patients with SS had a low 5-year overall survival of 33.5% vs 64.5% in their controls (p = 0.0046), whereas 62.3% of patients with MF were alive 10 years after diagnosis vs 71.4% of their controls (p = 0.0011). SS diagnosis (hazard ratio [HR] 11.85 [5.08, 27.65]; p < 0.001) and higher age (HR 1.07 [1.01, 1.12]; p = 0.01) were risk factors of poorer disease-specific survival. Moreover, patients with MF had a 2.38-fold [1.07, 5.27] risk of thyroid diseases (p = 0.033) and over 1.5-fold [1.17, 2.07] risk of cardiovascular diseases (p = 0.002) compared with controls. In conclusion, in the Finnish population, patients with MF or SS had a higher incidence and mortality and more late comorbidities than controls. More awareness, earlier diagnostic tools, and more effective treat-ment for MF/SS are needed.

Indexed as

Mycosis FungoidesSezary SyndromeSkin NeoplasmsAdolescentAdultAgedAged, 80 and overCase-Control StudiesCause of DeathFemaleFinlandHumansIncidenceMaleMiddle AgedRegistries

Identifiers

PMID41508834
PMCPMC12797152

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.