ArticleInfectious diseases of poverty2026
Schistosomiasis japonica transmission dynamics: mathematical modeling in guiding One Health approach control strategies.
Article in Infectious diseases of poverty, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
Abstract
purposeSchistosomiasis (SCH) japonica remains a persistent public health concern in the Philippines despite continuing control efforts. This study aims to examine the transmission dynamics of SCH japonica and evaluate different intervention strategies using a One Health modeling approach, with the goal of supporting feasible control and elimination targets.
methodsWe developed a compartmental mathematical model calibrated using field survey data collected in 2022 from eight endemic barangays in Agusan del Sur and Surigao del Norte. The dataset included SCH prevalence, egg excretion levels in humans and animals quantified through Kato-Katz, modified McMaster, and sedimentation techniques, and household distance to potential transmission sites. Multiple intervention strategies were examined, including human and animal chemotherapy, WaSH (water access, sanitation, and hygiene) adoption, pasture prohibition, vegetation clearing, and snail control. Sensitivity analysis using Partial Rank Correlation Coefficients (PRCC) was performed to identify influential transmission drivers.
resultsThe model estimates baseline prevalence at approximately 20% in humans across the study areas. Under medium WaSH adoption, human prevalence is projected to decline to approximately 1.01% by 2030, whereas high WaSH coverage further reduces prevalence to 0.64%. Combining WaSH and pasture prohibition alongside chemotherapy is projected to reduce human prevalence to 0.09% and animal prevalence to 0.10% by 2030. Sensitivity analysis identified snail-to-human transmission rate (PRCC = 0.612) and snail shedding rate (PRCC = 0.607) as the most influential parameters.
conclusionIntegrated strategies focusing on WaSH, reduced animal exposure, and targeted chemotherapy offer the most effective pathway toward achieving World Health Organization's (WHO's) 2030 SCH targets. Implementation should be strengthened through health education, behavioral interventions, mechanization support, and active Local Government Unit (LGU) participation.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.