Evidence map›Paper›PMID 41508055›Full record

ArticleActa neuropathologica communications2026

Genomic analysis of PLNTY-like tumor progression into epithelioid glioblastoma: a case report.

Sonja Mäntylä, Anssi Nurminen, Sanna Huovinen, Serafiina Jaatinen, Teppo Haapaniemi, Riikka Nurminen, Ismaïl Hermelo, Stefanie Volz, Kendra K Maaß, Kristian W Pajtler and 5 more

Abstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Acta neuropathologica communications, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Sonja MäntyläFaculty of Medicine and Health Technology, Tampere University, Arvo Ylpön Katu 34, 33520, Tampere, Finland.
Anssi NurminenFaculty of Medicine and Health Technology, Tampere University, Arvo Ylpön Katu 34, 33520, Tampere, Finland.
Sanna HuovinenFimlab Laboratories Ltd., Tampere University, Arvo Ylpön Katu 4, 33520, Tampere, Finland.
Serafiina JaatinenFaculty of Medicine and Health Technology, Tampere University, Arvo Ylpön Katu 34, 33520, Tampere, Finland.
Teppo HaapaniemiFimlab Laboratories Ltd., Tampere University, Arvo Ylpön Katu 4, 33520, Tampere, Finland.
Riikka NurminenFaculty of Medicine and Health Technology, Tampere University, Arvo Ylpön Katu 34, 33520, Tampere, Finland.
Ismaïl HermeloFaculty of Medicine and Health Technology, Tampere University, Arvo Ylpön Katu 34, 33520, Tampere, Finland.
Stefanie VolzHopp Children's Cancer Center Heidelberg (KiTZ), Heidelberg, Germany.
Kendra K MaaßHopp Children's Cancer Center Heidelberg (KiTZ), Heidelberg, Germany.
Kristian W PajtlerHopp Children's Cancer Center Heidelberg (KiTZ), Heidelberg, Germany.
Kristiina NordforsTAYS Cancer Center, Tampere University Hospital, Arvo Ylpön Katu 34, 33520, Tampere, Finland.
Hannu HaapasaloFimlab Laboratories Ltd., Tampere University, Arvo Ylpön Katu 4, 33520, Tampere, Finland.
Matti NykterFaculty of Medicine and Health Technology, Tampere University, Arvo Ylpön Katu 34, 33520, Tampere, Finland.
Joonas HaapasaloTAYS Cancer Center, Tampere University Hospital, Arvo Ylpön Katu 34, 33520, Tampere, Finland.
Kirsi J RautajokiFaculty of Medicine and Health Technology, Tampere University, Arvo Ylpön Katu 34, 33520, Tampere, Finland. kirsi.rautajoki@tuni.fi.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Polymorphous low-grade neuroepithelial tumors of the young (PLNTY) are slow- or non-progressing epileptogenic tumors, typically occurring in young adults. These tumors are highly calcified and exhibit both diffuse growth and oligodendroglioma-like patterns. Epithelioid glioblastomas (E-GB) are rare and aggressive variants of isocitrate dehydrogenase wildtype glioblastomas (GB), associated with poor overall survival. Both PLNTY and E-GB often carry oncogenic BRAF V600E mutation (BRAF

Indexed as

Brain NeoplasmsGlioblastomaAdultCyclin-Dependent Kinase Inhibitor p15Disease ProgressionFemaleGenomicsHumansMutationProto-Oncogene Proteins B-rafBRAF protein, humanCyclin-Dependent Kinase Inhibitor p15Proto-Oncogene Proteins B-rafBrain tumorCancerCancer geneticsEpithelioid glioblastomaPolymorphous-low-grade-neuroepithelial-of-young

Identifiers

PMID41508055
PMCPMC12874860

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.