Evidence map›Paper›PMID 41508036›Full record

ArticleHead & face medicine2026

Apical root resorption in Class III patients following pronounced mandibular incisor retraction with lingual high precision fixed appliances: a retrospective cohort study.

Julia von Bremen, Dimitrios Kloukos, Collin Jacobs, Lara Bettenhäuser-Hartung, Jonas Q Schmid

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Article in Head & face medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

5 authors.

Julia von BremenPrivate Practice, Bad Essen, Germany.
Dimitrios KloukosDepartment of Orthodontics and Dentofacial Orthopedics, University of Bern, Bern, Switzerland.
Collin JacobsDepartment of Orthodontics, Heinrich Heine University, Düsseldorf, Germany.
Lara Bettenhäuser-HartungDepartment of Orthodontics, Hannover Medical School, Hannover, Germany.
Jonas Q SchmidDepartment of Orthodontics, University of Münster, Münster, Germany. jonasquirin.schmid@ukmuenster.de.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundExtensive retraction of mandibular incisors in Class III treatment may increase the risk of orthodontically induced apical root resorption (OIARR). This retrospective cohort study aimed to assess the incidence and severity of OIARR in Class III patients treated nonsurgically with lingual high precision fixed appliances (HPFAs) and significant anterior tooth retraction.

methodsEligible for inclusion were adolescent and adult Class III patients treated with lingual HPFAs (WIN, DW Lingual Systems GmbH) and extraction of lower premolars, who completed treatment between 2015 and 2024. Pre- (T0) and post-treatment (T1) panoramic radiographs were measured for root and crown lengths, with relative root resorption (rRR, %) calculated for each tooth. Clinically relevant OIARR was assessed using the Malmgren index (scores 1-4). Statistical significance of mean rRR (%) changes was assessed using one-sample t-tests (α = 0.05).

resultsA total of 25 patients (mean age at T1 26.8 ± 9.7 years; 12 females, 13 males; mean Wits at T0 -6.7 ± 2.5 mm) and 350 mandibular teeth were analyzed. The mean rRR for anterior teeth was 3.15 ± 4.05%, with no cases of severe resorption (Malmgren score 4) and only 6.7% of roots exhibiting clinically relevant shortening (Malmgren score 3). There was no increased risk of OIARR in anterior teeth compared to premolars and molars (3.15% vs. 3.31%).

conclusionExtensive bodily retraction of lower anterior teeth was not associated with significant OIARR in this Class III cohort. Excellent torque control using HPFAs enabled considerable retraction with low risk of OIARR, supporting this approach as a safe nonsurgical alternative for Class III camouflage.

Indexed as

IncisorMalocclusion, Angle Class IIIOrthodontic Appliances, FixedRoot ResorptionTooth Movement TechniquesAdolescentAdultCohort StudiesFemaleHumansMaleRadiography, PanoramicRetrospective StudiesYoung AdultCamouflageCCLAClass III treatmentCompletely customized lingual appliancesHigh precision fixed appliancesHPFAOIARROrthodontically induced apical root resorptions

Identifiers

PMID41508036
PMCPMC12849116

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.