Evidence map›Paper›PMID 41508020›Full record

ReviewChinese medicine2026

Development and application of artificial intelligence in traditional Chinese medicine research and development.

Anxin Wang, Qiaoxian Luo, Xiaotian Tan, Yixin Yao, Xuebo Peng, Hua Luo, Yuanjia Hu

Abstract readReview
In one paragraph

Review in Chinese medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Anxin Wang *State Key Laboratory of Mechanism and Quality of Chinese Medicine, Institute of Chinese Medical Sciences, University of Macau, Macao SAR, China.
Qiaoxian Luo *State Key Laboratory of Mechanism and Quality of Chinese Medicine, Institute of Chinese Medical Sciences, University of Macau, Macao SAR, China.
Xiaotian TanState Key Laboratory of Mechanism and Quality of Chinese Medicine, Institute of Chinese Medical Sciences, University of Macau, Macao SAR, China.
Yixin YaoState Key Laboratory of Mechanism and Quality of Chinese Medicine, Institute of Chinese Medical Sciences, University of Macau, Macao SAR, China.
Xuebo PengGuangdong Foshan Joint Key Laboratory for the Research and Development and Industrialization of Chinese Medicinal Formulations, Foshan, 528000, China.
Hua LuoState Key Laboratory of Mechanism and Quality of Chinese Medicine, Institute of Chinese Medical Sciences, University of Macau, Macao SAR, China. hualuo@um.edu.mo.
Yuanjia HuState Key Laboratory of Mechanism and Quality of Chinese Medicine, Institute of Chinese Medical Sciences, University of Macau, Macao SAR, China. yuanjiahu@um.edu.mo.

Funding

University of Macau Zhuhai UM Science and Technology Research Institute HUMRI-CP-101-2024
6 · The paper itself

Abstract

backgroundThe integration of artificial intelligence (AI) into traditional Chinese medicine (TCM) research and development offers promising solutions to longstanding challenges in the field. These challenges include the complexity of TCM formulations, variability in quality control, and hurdles in global market acceptance. The unique synergy between AI technologies and TCM principles creates opportunities to enhance research efficiency, standardization, and innovation. AIM OF REVIEW: This review aims to explore the applications and impact of AI across three critical stages of TCM development: drug design, pharmaceutical manufacturing, and market access. By summarizing the advancements and limitations in these areas, the review identifies the transformative potential of AI and proposes future directions for integrating AI with emerging technologies to advance TCM research and development (R&D). KEY SCIENTIFIC CONCEPTS OF REVIEW: AI has transformative potential in TCM development, addressing key challenges across various stages. In drug design, AI accelerates the identification of active compounds, optimizes formula composition, and models pharmacodynamic relationships to enhance innovation efficiency and precision. During pharmaceutical manufacturing, AI contributes to process optimization, quality control, and the standardization of TCM products, ensuring stable and scalable production. For market access, although no TCM developed by AI has entered the clinic, AI has played a role in comprehensive safety and efficacy assessments and simplified regulatory compliance in other drugs. By leveraging these advances and reviewing limitations, AI promotes the need to develop more integrated, more efficient, and more utilized methods in TCM R&D.

Indexed as

AIDeep learningDrug designMachine learningTCM R&D

Identifiers

PMID41508020
PMCPMC12781431

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.