ArticleNeurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology2026
Are cervical vestibular evoked myogenic potential (cVEMP) sensitive enough for the evaluation of patients with relapsing-remitting multiple sclerosis?
Article in Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundMultiple sclerosis (MS) is a long-term neurological condition that impacts the brain and spinal cord. The infratentorial area houses the cerebellum and brainstem. Vestibular evoked myogenic potentials (VEMPs) are myogenic responses with short latency. Cervical vestibular evoked myogenic potential (cVEMP) represents a reflection of the vestibulocolic reflex.
methodsA total of 32 consecutive patients participated in the study (males, n = 12; females, n = 20). Cervical VEMP (cVEMP) were examined for latencies, conduction block, and amplitude asymmetry ratio, and the VEMP score was determined. MRI was examined for brainstem lesions collectively and individually for lesions in the pons, midbrain, and medulla oblongata. Their findings were compared to those of 32 healthy individuals.
resultsIn the research, 5 RRMS patients (2.1%) exhibited no reaction in the cVEMP test for both the right and left ear (as explained in Tables 1 and 2). The average latencies for P1 and N1 in the left ears of RRMS patients were notably greater than those in the control group, yielding p-values of 0.001 and 0.002, respectively. Nevertheless, there was no notable difference in the P1-N1 interval or mean amplitude of the left ear when comparing patients and controls (p > 0.05). Conversely, the P1 and N1 latencies, as well as the average P1-N1 interval for the patients' right ears, were notably greater than those of the control group, with p-values of 0.01, 0.001, and 0.004, respectively. Extended latencies for P1 and N1 were noted in 42 (65%) of the 64 RRMS ears and in 27 ears (42%), respectively.
conclusionVestibular evoked myogenic potential has a high sensitivity (70%) in MS patients, and VEMP could be recommended as a useful complementary neurophysiological method to evaluate the MS patients.
Indexed as
Identifiers
41507616What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.