Evidence map›Paper›PMID 41507611›Full record

ArticleJournal of neurology2026

Duration of EEG monitoring needed to ensure a low risk of seizure recurrence in hospitalized patients.

Parimala Velpula Krishnamurthy, Santiago Philibert-Rosas, Maxwell Rivkin, Cameron J Brace, Steven E Haworth, Safoora Fatima, Atakan Selte, Mariel Kalkach Aparicio, Aaron F Struck

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In one paragraph

Article in Journal of neurology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Parimala Velpula Krishnamurthy *Department of Neurology, University of Wisconsin - Madison, Madison, WI, USA.ORCID http://orcid.org/0000-0001-6140-9692
Santiago Philibert-Rosas *Department of Neurology, University of Wisconsin - Madison, Madison, WI, USA.ORCID http://orcid.org/0000-0002-2521-334X
Maxwell RivkinDepartment of Neurology, University of Wisconsin - Madison, Madison, WI, USA.ORCID http://orcid.org/0009-0003-0828-5039
Cameron J BraceDepartment of Neurology, University of Wisconsin - Madison, Madison, WI, USA.ORCID http://orcid.org/0009-0002-2350-6939
Steven E HaworthDepartment of Neurology, University of Wisconsin - Madison, Madison, WI, USA.ORCID http://orcid.org/0009-0006-5743-811X
Safoora FatimaDepartment of Neurology, Southern Illinois University, Springfield, IL, USA.ORCID http://orcid.org/0000-0002-2274-6685
Atakan SelteDepartment of Neurology, University of California Los Angeles - Harbor, Los Angeles, CA, USA.
Mariel Kalkach AparicioDepartment of Neurology, Sanford Medical Center, University of South Dakota, Sioux Falls, SD, USA.ORCID http://orcid.org/0000-0002-3509-3548
Aaron F StruckDepartment of Neurology, University of Wisconsin - Madison, Madison, WI, USA. struck@wustl.edu.ORCID http://orcid.org/0000-0002-9103-1798

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundContinuous EEG (cEEG) monitoring is critical for detecting seizures in hospitalized patients, but optimal durations of EEG monitoring remain unclear, particularly after a seizure has been detected on monitoring.

methodsWe conducted survival analysis on 117 patients with electrographic or electroclinical seizures who underwent cEEG at the University of Wisconsin Hospital (UWH) between 2018 and 2022. Time from the end of seizure-to-seizure recurrence or cEEG termination was analyzed using Cox regression.

resultsIn univariate analysis, status epilepticus (SE) was the only clinical feature significantly associated with increased risk of seizure recurrence (P = 0.022). The estimated EEG duration required to reduce seizure recurrence risk below 5% was 36.8 h in patients with SE and 21.2 h in those without SE. Numerous other clinical variables, including coma, antiseizure medications addition, use of anesthetic infusions, history of epilepsy, and epileptiform discharges, were not significant.

conclusionOur findings support current clinical practices of at least 24 h of EEG monitoring following seizure cessation and highlight that patients with a history of status epilepticus may require longer monitoring. These data reinforce the value of individualized, risk-based approaches to EEG monitoring strategies.

Indexed as

ElectroencephalographyNeurophysiological MonitoringSeizuresStatus EpilepticusAdultAgedFemaleHospitalizationHumansMaleMiddle AgedRecurrenceRetrospective StudiesTime FactorsContinious electroencephalogram (cEEG)EEG monitoringSeizure recurranceStatus epilepticus

Identifiers

PMID41507611
PMCPMC12783230

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.