Evidence map›Paper›PMID 41507579›Full record

ArticleGraefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie2026

Automatic measurement and evaluation of anterior segment anatomical structures via UBM images using a deep learning-based approach.

Sijing Chen, Xiaoran Chu, Emmanuel Eric Pazo, Yue Huang, Hui Liu, Chen Zhang, Ruibo Yang, Shaozhen Zhao

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In one paragraph

Article in Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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5 · Who and what money

Authors and funding

8 authors.

Sijing Chen *Tianjin Key Laboratory of Retinal Functions and Diseases, Tianjin Branch of National Clinical Research Center for Ocular Disease, Eye Institute and School of Optometry, Tianjin Medical University Eye Hospital, Tianjin, China.
Xiaoran Chu *Tianjin Key Laboratory of Retinal Functions and Diseases, Tianjin Branch of National Clinical Research Center for Ocular Disease, Eye Institute and School of Optometry, Tianjin Medical University Eye Hospital, Tianjin, China.
Emmanuel Eric PazoTianjin Key Laboratory of Retinal Functions and Diseases, Tianjin Branch of National Clinical Research Center for Ocular Disease, Eye Institute and School of Optometry, Tianjin Medical University Eye Hospital, Tianjin, China.
Yue HuangTianjin Key Laboratory of Retinal Functions and Diseases, Tianjin Branch of National Clinical Research Center for Ocular Disease, Eye Institute and School of Optometry, Tianjin Medical University Eye Hospital, Tianjin, China.
Hui LiuTianjin Key Laboratory of Retinal Functions and Diseases, Tianjin Branch of National Clinical Research Center for Ocular Disease, Eye Institute and School of Optometry, Tianjin Medical University Eye Hospital, Tianjin, China.
Chen ZhangTianjin Key Laboratory of Retinal Functions and Diseases, Tianjin Branch of National Clinical Research Center for Ocular Disease, Eye Institute and School of Optometry, Tianjin Medical University Eye Hospital, Tianjin, China.
Ruibo YangTianjin Key Laboratory of Retinal Functions and Diseases, Tianjin Branch of National Clinical Research Center for Ocular Disease, Eye Institute and School of Optometry, Tianjin Medical University Eye Hospital, Tianjin, China.
Shaozhen ZhaoTianjin Key Laboratory of Retinal Functions and Diseases, Tianjin Branch of National Clinical Research Center for Ocular Disease, Eye Institute and School of Optometry, Tianjin Medical University Eye Hospital, Tianjin, China. zhaosz1997@sina.com.

Funding

National Natural Science Foundation of China 82271062Tianjin Key Medical Discipline Construction Project TJYXZDXK-3-004A-2
6 · The paper itself

Abstract

purposeTo develop a deep-learning model capable of measuring essential anterior segment (AS) parameters derived from preoperative ultrasound biomicroscopy (UBM) images of candidates for implantable collamer lens (ICL) surgery.

settingTianjin Medical University Eye Hospital, Tianjin, China.

designCross-sectional retrospective study.

methodsA dataset comprising 1,480 preoperative panoramic UBM images taken from 638 eyes of 320 subjects was collected and was divided into training and testing subsets at a proportion of 7:3. Using the YOLOv8-pose algorithm, the model identified ten anatomical key point coordinates and computed six relevant AS parameters. Both manual and anterior segment optical coherence tomography-based non-contact measurements served as reference standards for evaluating the model's accuracy. The relationship between postoperative vault and preoperative parameters measured by the model was analyzed using multiple linear regression.

resultsOn the test dataset, the model achieved an intraclass correlation coefficient (ICC) exceeding 0.978, with a mean Euclidean distance of 67.65 ± 54.25 μm across all point locations. The ICC values for anterior chamber depth (ACD), pupil diameter, and sulcus-to-sulcus distance were above 0.980 (95% CI: 0.975 to 0.985), with average relative error below 1.7%. Additionally, postoperative vault at one month was significantly correlated with model-measured parameters, including crystalline lens rise, iris concavity, and ACD (P < 0.001).

conclusionThis study introduces a robust program capable of quantitatively measuring AS parameters with accuracy comparable to that of experienced ophthalmologists. The findings provide valuable guidance for ICL sizing and vault prediction.

Indexed as

Anterior Eye SegmentDeep LearningMicroscopy, AcousticMyopiaPhakic Intraocular LensesAdultCross-Sectional StudiesFemaleHumansLens Implantation, IntraocularMaleMiddle AgedRetrospective StudiesTomography, Optical CoherenceYoung AdultAnatomical biomarkersDeep learningImplantable collamer lensUltrasound biomicroscopy

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.