Evidence map›Paper›PMID 41507570›Full record

ArticleCommunications biology2026

Transient receptor potential canonical 3 is required for HPV-induced malignant transformation of cervical epithelial cells.

Yudi Tan, Qiaoqiao Huang, Jingjing Zeng, Yong Wang, Shasha Yang, Li Yu, Jinkong Wei, Yuying Wei, Jinmin Zhao, Junying Chen

Abstract read
In one paragraph

Article in Communications biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Yudi Tan *Department of Obstetrics and Gynecology, The First Affiliated Hospital of Guangxi Medical University, Nanning, China.
Qiaoqiao Huang *Department of Obstetrics and Gynecology, The First Affiliated Hospital of Guangxi Medical University, Nanning, China.
Jingjing ZengDepartment of Pathology, The First Affiliated Hospital of Guangxi Medical University, Nanning, China.
Yong WangDepartment of Obstetrics and Gynecology, The First Affiliated Hospital of Guangxi Medical University, Nanning, China.
Shasha YangDepartment of Obstetrics and Gynecology, The First Affiliated Hospital of Guangxi Medical University, Nanning, China.
Li YuDepartment of Obstetrics and Gynecology, The First Affiliated Hospital of Guangxi Medical University, Nanning, China.
Jinkong WeiDepartment of Obstetrics and Gynecology, The First Affiliated Hospital of Guangxi Medical University, Nanning, China.
Yuying WeiDepartment of Obstetrics and Gynecology, The First Affiliated Hospital of Guangxi Medical University, Nanning, China.
Jinmin ZhaoSchool of Basic Medicine Science, Guangxi Medical University, Nanning, China. zhaojinmin@gxmu.edu.cn.
Junying ChenDepartment of Obstetrics and Gynecology, The First Affiliated Hospital of Guangxi Medical University, Nanning, China. chenjunying@gxmu.edu.cn.ORCID http://orcid.org/0000-0003-1969-9416

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Human Papillomavirus (HPV) types 16 and 18 are well-established causative agents in cervical cancer. However, the mechanism of malignant transformation remains unclear. Although epithelial-mesenchymal transition (EMT) is regulated by Ca

Indexed as

Cell Transformation, NeoplasticCervix UteriEpithelial CellsPapillomavirus InfectionsTRPC Cation ChannelsUterine Cervical NeoplasmsAnimalsEpithelial-Mesenchymal TransitionFemaleHuman papillomavirus 16HumansMiceMice, Inbred BALB CTRPC3 cation channelTRPC Cation Channels

Identifiers

PMID41507570
PMCPMC12891719

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.