Evidence map›Paper›PMID 41507489›Full record

ArticleBulletin of experimental biology and medicine2025

Erythropoiesis-Stimulating Action of Anthocyan-Containing Complex from Aronia melanocarpa (Michx.) Elliott in Experimental Cytostatic Therapy.

O Yu Rybalkina, E P Fedorova, A V Chaikovskii, N S Selivanova, T G Razina, G I Kalinkina, V Yu Andreeva, O V Voronkova, E P Zueva, M V Belousov and 1 more

Abstract read
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Article in Bulletin of experimental biology and medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

O Yu RybalkinaGoldberg Research Institute of Pharmacology and Regenerative Medicine, Tomsk National Research Medical Center, Russian Academy of Sciences, Tomsk, Russia. olgatomsk87@gmail.com.
E P FedorovaGoldberg Research Institute of Pharmacology and Regenerative Medicine, Tomsk National Research Medical Center, Russian Academy of Sciences, Tomsk, Russia.
A V ChaikovskiiGoldberg Research Institute of Pharmacology and Regenerative Medicine, Tomsk National Research Medical Center, Russian Academy of Sciences, Tomsk, Russia.
N S SelivanovaGoldberg Research Institute of Pharmacology and Regenerative Medicine, Tomsk National Research Medical Center, Russian Academy of Sciences, Tomsk, Russia.
T G RazinaGoldberg Research Institute of Pharmacology and Regenerative Medicine, Tomsk National Research Medical Center, Russian Academy of Sciences, Tomsk, Russia.
G I KalinkinaSiberian State Medical University, Ministry of Health of the Russian Federation, Tomsk, Russia.
V Yu AndreevaSiberian State Medical University, Ministry of Health of the Russian Federation, Tomsk, Russia.
O V VoronkovaSiberian State Medical University, Ministry of Health of the Russian Federation, Tomsk, Russia.
E P ZuevaGoldberg Research Institute of Pharmacology and Regenerative Medicine, Tomsk National Research Medical Center, Russian Academy of Sciences, Tomsk, Russia.
M V BelousovSiberian State Medical University, Ministry of Health of the Russian Federation, Tomsk, Russia.
V V ZhdanovGoldberg Research Institute of Pharmacology and Regenerative Medicine, Tomsk National Research Medical Center, Russian Academy of Sciences, Tomsk, Russia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We studied the effect of an anthocyanin-containing complex from Aronia melanocarpa (Michx.) Elliott on the main indicators of erythropoiesis in the peripheral blood and bone marrow of mice with Lewis lung carcinoma against the background of doxorubicin treatment. It was found that administration of the anthocyanin-containing complex from A. melanocarpa (Michx.) Elliott to tumor-bearing animals prevents the development of anemic syndrome via stimulation of the erythropoiesis recovery after its inhibition by the cytostatic agent. The mechanisms of erythropoiesis stimulation by the plant-derived complex involve systems of local and distant regulation of proliferation and differentiation of committed erythroid progenitor cells.

Indexed as

AnthocyaninsCarcinoma, Lewis LungCytostatic AgentsErythropoiesisPhotiniaPlant ExtractsAnemiaAnimalsCell DifferentiationCell ProliferationDoxorubicinErythroid Precursor CellsMiceMice, Inbred C57BLAnthocyaninsCytostatic AgentsDoxorubicinPlant Extractsanemic syndromeanthocyaninsdoxorubicinregenerationtumor

Identifiers

PMID41507489

What OpenQuestion holds

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.