Evidence map›Paper›PMID 41507485›Full record

ArticleBulletin of experimental biology and medicine2025

Methanogen Methanosphaera stadtmanae in Women Intestine. Influence on Free Radical Oxidation and Sleep Quality in Menopause.

N V Semenova, N E Garashchenko, N L Belkova, O A Nikitina, E A Novikova, N E Smurova, E S Klimenko, S I Kolesnikov, I M Madaeva, L I Kolesnikova

Abstract read
PubMed Publisher
In one paragraph

Article in Bulletin of experimental biology and medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Sleep Disorders in Climacteric Women: Glutathione, Glutathione S-Transferase P1 and Gut Microbiome Interrelation.Pathophysiology : the official journal of the International Society for Pathophysiology · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

N V SemenovaScientific Centre for Family Health and Human Reproduction Problems, Irkutsk, Russia. natkor_84@mail.ru.
N E GarashchenkoScientific Centre for Family Health and Human Reproduction Problems, Irkutsk, Russia.
N L BelkovaScientific Centre for Family Health and Human Reproduction Problems, Irkutsk, Russia.
O A NikitinaScientific Centre for Family Health and Human Reproduction Problems, Irkutsk, Russia.
E A NovikovaScientific Centre for Family Health and Human Reproduction Problems, Irkutsk, Russia.
N E SmurovaScientific Centre for Family Health and Human Reproduction Problems, Irkutsk, Russia.
E S KlimenkoScientific Centre for Family Health and Human Reproduction Problems, Irkutsk, Russia.
S I KolesnikovScientific Centre for Family Health and Human Reproduction Problems, Irkutsk, Russia.
I M MadaevaScientific Centre for Family Health and Human Reproduction Problems, Irkutsk, Russia.
L I KolesnikovaScientific Centre for Family Health and Human Reproduction Problems, Irkutsk, Russia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The correlation between the products of oxidative modification of lipids, proteins, DNA and sleep quality and the presence of the methanogen Methanosphaera stadtmanae in the intestine was assessed in 98 menopausal women. Higher levels of thiobarbituric acid-reactive substances (TBARS) and end-products of protein oxidation were found in the group with sleep disorders (Pittsburgh Sleep Quality Index) in comparison with the control in the sample with M. stadtmanae in the intestine. The presence of this microorganism is associated with a lower level of 8-hydroxy-2'-deoxyguanosine (8-OHdG) in the total sample, as well as in the control group, while for the group with sleep disorders, M. stadtmanae is associated with a higher level of TBARS and Schiff bases. The results indicate possible interaction between M. stadtmanae from the intestine and oxidative processes in the body.

Indexed as

IntestinesMenopauseMethanobacteriaceaeSleep QualitySleep Wake Disorders8-Hydroxy-2'-DeoxyguanosineDeoxyguanosineFemaleFree RadicalsHumansMiddle AgedOxidation-ReductionOxidative StressThiobarbituric Acid Reactive Substances8-Hydroxy-2'-DeoxyguanosineDeoxyguanosineFree RadicalsThiobarbituric Acid Reactive Substancesfree radical oxidationmenopauseMethanosphaera stadtmanaesleep disorders

Identifiers

PMID41507485

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.