Evidence map›Paper›PMID 41507481›Full record

ArticleBulletin of experimental biology and medicine2025

Immunohistochemical Detection of Connexin-43 in the Myocardium of Preterm Born Rats.

V V Ivanova, O N Serebryakova, A V Erokhina, A D Nikonova, I V Milto

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Article in Bulletin of experimental biology and medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

V V IvanovaSiberian State Medical University, Ministry of Health of the Russian Federation, Tomsk, Russia. ivvera92@rambler.ru.
O N SerebryakovaSiberian State Medical University, Ministry of Health of the Russian Federation, Tomsk, Russia.
A V ErokhinaSiberian State Medical University, Ministry of Health of the Russian Federation, Tomsk, Russia.
A D NikonovaSiberian State Medical University, Ministry of Health of the Russian Federation, Tomsk, Russia.
I V MiltoSiberian State Medical University, Ministry of Health of the Russian Federation, Tomsk, Russia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

An immunohistochemical study of connexin-43 (Cx43) was carried out in the myocardium of the left ventricle of 6-month-old rats born one day preterm. Using computer morphometry, the relative area of immunopositive staining was determined. The intensity of immunopositive staining was evaluated spectrophotometrically. It was shown that in preterm born 6-month-old rats, Cx43 is located in the region of intercalated discs. However, the relative area, as well as the intensity of Cx43-positive staining in this case was lower than in full-term animals. Thus, preterm birth affects the expression of Cx43 in the myocardium in the late postnatal period.

Indexed as

Connexin 43MyocardiumPremature BirthAnimalsAnimals, NewbornFemaleHeart VentriclesImmunohistochemistryMaleRatsRats, WistarConnexin 43connexin-43intercalated diskmyocardiumpreterm birth

Identifiers

PMID41507481

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.