Evidence map›Paper›PMID 41507409›Full record

ArticleScientific reports2026

Exploring acute physiological adaptations to circuit strength training: the role of work-to-rest interval variations.

Aaron Agudo-Ortega, Marcos Gomez-Castro, Rafael Olivares-Llorente, Adrián Martín-Castellanos, Manuel Barba-Ruíz, Francisco Hermosilla-Perona

Abstract read
In one paragraph

Article in Scientific reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Aaron Agudo-OrtegaFacultad de Ciencias Biomédicas y de la Salud, Universidad Alfonso X el Sabio (UAX), Avenida de la Universidad, 1, 28691, Villanueva de la Cañada, Madrid, Spain.ORCID http://orcid.org/0000-0002-4087-1447
Marcos Gomez-CastroFacultad de Ciencias Biomédicas y de la Salud, Universidad Alfonso X el Sabio (UAX), Avenida de la Universidad, 1, 28691, Villanueva de la Cañada, Madrid, Spain.ORCID http://orcid.org/0009-0001-8016-0375
Rafael Olivares-LlorenteFacultad de Ciencias Biomédicas y de la Salud, Universidad Alfonso X el Sabio (UAX), Avenida de la Universidad, 1, 28691, Villanueva de la Cañada, Madrid, Spain.ORCID http://orcid.org/0009-0005-2277-401X
Adrián Martín-CastellanosFacultad de Ciencias Biomédicas y de la Salud, Universidad Alfonso X el Sabio (UAX), Avenida de la Universidad, 1, 28691, Villanueva de la Cañada, Madrid, Spain.ORCID http://orcid.org/0000-0002-1037-4319
Manuel Barba-RuízFacultad de Ciencias Biomédicas y de la Salud, Universidad Alfonso X el Sabio (UAX), Avenida de la Universidad, 1, 28691, Villanueva de la Cañada, Madrid, Spain.ORCID http://orcid.org/0000-0002-4840-1263
Francisco Hermosilla-PeronaFacultad de Ciencias Biomédicas y de la Salud, Universidad Alfonso X el Sabio (UAX), Avenida de la Universidad, 1, 28691, Villanueva de la Cañada, Madrid, Spain. fperoher@uax.es.ORCID http://orcid.org/0000-0002-7069-5798

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We investigated the acute physiological responses to circuit strength training performed with different work-to-rest interval durations (10:10, 20:20, and 30:30 s) under a constant 1:1 ratio. Thirty-four trained adults (15 males and 19 females) completed a 14-min circuit protocol consisting of two blocks of 6-min separated by a 2-min rest period. Each session included six alternating upper- and lower-body exercises performed at maximal intended velocity. Heart rate (HR) was continuously monitored during the protocol, while blood lactate concentration, countermovement jump (CMJ) height, and 10-m sprint performance were assessed pre-, mid-, and post-circuit session. Repeated-measures ANOVA was used for CMJ height, blood lactate concentration and 10-m sprint performance, and one-way ANOVA for HR data. The 30:30 protocol elicited the highest post-exercise lactate concentrations (p < 0.05) and the largest decrements in CMJ height. In contrast, HR was consistently higher in the 10:10 protocol across several time points (p < 0.01), indicating greater cardiovascular demand. Sprint performance declined from pre- to post-exercise across all protocols, indicating a time-dependent fatigue response. These findings demonstrate that manipulating absolute work-to-rest durations, even under a fixed 1:1 ratio, produces distinct physiological responses, while performance decrements may occur independently of protocol configuration. Longer intervals (30:30) maximize metabolic stress and neuromuscular fatigue, whereas shorter intervals (10:10) enhance cardiovascular load. The 20:20 protocol represents a balanced alternative between both stimuli.

Indexed as

Adaptation, PhysiologicalResistance TrainingRestAdultFemaleHeart RateHumansLactic AcidMaleYoung AdultLactic AcidCircuit trainingFatigueHeart rateLactateWork-to-rest ratio

Identifiers

PMID41507409
PMCPMC12873116

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.