ArticleScientific reports2026
An aptamer-functionalized AuNPs/rGO nanocomposite biosensor for ultrasensitive detection of foodborne pathogen E. coli O157:H7.
Article in Scientific reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- A Monolithic, Thiol-Functionalized Au-Based Bio-CMOS Aptasensor for Rapid, Label-Free Detection ofBioengineering (Basel, Switzerland) · 2026Article
- Bacterial species differentiation via real-time detection of microbial volatile organic compounds using a wavelength multiplexed photoionization detector and AI image-based analysis.Scientific reports · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Foodborne pathogenic bacteria can cause food poisoning or infection, leading to disease. Early screening of foodborne pathogens has become crucial for managing and preventing these diseases. Here, we developed an electrochemical aptamer-based biosensor to detect Escherichia coli (E. coli O157:H7) in real samples. The glassy carbon electrode (GCE) underwent an initial treatment using a nanocomposite made of reduced graphene oxide (rGO) and gold nanoparticles (AuNPs) (AuNPs/rGO/GCE) to enhance the surface area and boost the sensor’s sensitivity. In addition to good electrical properties, nanocomposites made of rGO and AuNPs play a crucial role in sensor development by enabling high loading and adequate immobilization of biorecognition elements like aptamers while preserving their activity and affinity. Next, to elevate the specificity of the altered electrode, aptamers were linked to the exterior of the prepared electrode (APT/AuNPs/rGO/GCE). The prepared electrode underwent characterization using field emission scanning electron microscopy, energy-dispersive spectroscopy, Fourier-transform infrared spectroscopy, and electrochemical impedance spectroscopy. This proposed aptasensor can accurately identify E. coli O157:H7 within a range of 6 to 6 × 108 CFU/mL and has a detection limit of 3.25 CFU/mL. Microbial culture results validate the aptasensor findings, providing quicker results and a lower detection limit.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.