Evidence map›Paper›PMID 41507152›Full record

ArticleCell death discovery2026

TFAM signaling molecule alleviates mitochondrial damage of cerebral ischemia-reperfusion.

Wenjun Wang, Yibiao Shi, Sitian Qiu, Ying Song, Xi Chen, Xiaomin Zhang, Beibei Wang, Qisong Li, Qiwen Shi

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Cell death discovery, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Wenjun Wang *Department of Pharmacology, Zhejiang University of Technology, Hangzhou,, 310014, Zhejiang, China.
Yibiao Shi *Department of Pharmacology, Zhejiang University of Technology, Hangzhou,, 310014, Zhejiang, China.
Sitian QiuDepartment of Pharmacology, Zhejiang University of Technology, Hangzhou,, 310014, Zhejiang, China.
Ying SongDepartment of Pharmacology, Zhejiang University of Technology, Hangzhou,, 310014, Zhejiang, China. songying@zjut.edu.cn.ORCID http://orcid.org/0000-0002-9798-7782
Xi ChenDepartment of Pharmacology, Zhejiang University of Technology, Hangzhou,, 310014, Zhejiang, China.ORCID http://orcid.org/0009-0009-7626-5922
Xiaomin ZhangThe First People's Hospital of Linping District, Hangzhou, Zhejiang, China.
Beibei WangDepartment of Pharmacology, Zhejiang University of Technology, Hangzhou,, 310014, Zhejiang, China.
Qisong LiChongqing Industry and Information Vocational College, Chongqing, China.
Qiwen ShiDepartment of Pharmacology, Zhejiang University of Technology, Hangzhou,, 310014, Zhejiang, China.

Funding

National Natural Science Foundation of China (National Science Foundation of China) 82174038Natural Science Foundation of Zhejiang Province (Zhejiang Provincial Natural Science Foundation) LD22H090002
6 · The paper itself

Abstract

In the present study, we aimed to investigate the antioxidant and therapeutic protective effects of carvacryl acetate (CAA) on Mitochondrial damage of cerebral ischemia-reperfusion through mitochondrial transcription factor A (TFAM) signaling molecules.SD rats were used to establish the middle cerebral artery occlusion (MCAO) model in vivo, and PC12 cells were stimulated with H

Identifiers

PMID41507152
PMCPMC12877106

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.