ArticleNature communications2026
Efficacy of two rounds of albendazole treatment on soil-transmitted helminths in schoolchildren, Yunnan Province, China.
Article in Nature communications, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
17 authors.
Funding
Abstract
Mass drug administration (MDA) of albendazole to at-risk populations remains the primary strategy for controlling soil-transmitted helminths (STH). Despite its widely use, its efficacy varies among different STH species and remains sub-optimal, particularly in the treatment of T. trichiura. Currently, studies investigating the optimal dose and regimens for albendazole are lacking. A longitudinal cohort study was conducted to assess the efficacy of two single-dose albendazole 400 mg treatments given four weeks apart targeting STH infections compared with just one single-dose albendazole 400 mg on 375 schoolchildren in Bulang Shan, Menghai county, Yunnan Province, China from October to December 2015. The first round of albendazole resulted in cure rates (CR) of 92.5%, 63.1% and 5.1%, and egg reduction rates (ERR) of 99.2%, 87.9% and 41.1% for A. lumbricoides, hookworms and T. trichiura, respectively. With the second round, efficacy remains high against A. lumbricoides (98.9% CR), is increased against hookworm (92.2% CR), and remains low against T. trichiura (6.3% CR). The second round increased the ERR to 99.6%, 99.8% and 74.1% for the same species, respectively. In this setting, albendazole is thus highly effective against A. lumbricoides, reasonably effective against hookworm, but has low efficacy against T. trichiura following two rounds of treatment.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.