ArticleThe Journal of international medical research2026
Endoscopic assessment of the gastroesophageal junction for predicting gastroesophageal reflux disease.
Article in The Journal of international medical research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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6 authors.
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Abstract
ObjectiveThis study was conducted to evaluate the predictive value of endoscopic measurements of cardia opening diameter and sliding hernia length for diagnosing gastroesophageal reflux disease.MethodsA total of 233 patients with typical gastroesophageal reflux disease symptoms who underwent endoscopy and esophageal pH-impedance monitoring between September 2017 and September 2023 were enrolled in this study. Cardia opening diameter and sliding hernia length were measured during endoscopy under adequate gastric insufflation. Using esophageal pH-impedance monitoring as the gold standard (with acid exposure time >4% as the diagnostic criterion for gastroesophageal reflux disease), the correlation between cardia opening diameter/sliding hernia length and gastroesophageal reflux disease-related parameters was analyzed. A nomogram prediction model was subsequently developed.ResultsThe optimal cutoff values for predicting pathological acid reflux were cardia opening diameter >2 cm and sliding hernia length >1 cm (area under the receiver operating characteristic curve = 0.648 for both). Compared with patients with a cardia opening diameter ≤2 cm, those with a cardia opening diameter >2 cm had significantly higher acid exposure time (6.8% vs. 2.5%), DeMeester score (25.7 vs. 10.9), and number of reflux episodes (108 vs. 59) (all
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