Evidence map›Paper›PMID 41506105›Full record

ArticleEnvironment international2026

Evaluating the effects of heat strain and air pollution on kidney health.

Jaime Butler-Dawson, Diana Jaramillo, Lyndsay Krisher, Karely Villarreal Hernandez, Laura Calvimontes, Grant Erlandson, James Seidel, Colton Castro, Stephen Brindley, Yaqiang Li and 10 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Environment international, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors.

Jaime Butler-DawsonCenters for Health, Work, & Environment, Colorado School of Public Health, University of Colorado, Anschutz Medical Campus, Aurora, CO, the United States of America; Department of Environmental and Occupational Health, Colorado School of Public Health, University of Colorado, Anschutz Medical Campus, Aurora, CO, the United States of America. Electronic address: Jaime.butler-dawson@cuanschutz.edu.
Diana JaramilloCenters for Health, Work, & Environment, Colorado School of Public Health, University of Colorado, Anschutz Medical Campus, Aurora, CO, the United States of America; Department of Environmental and Occupational Health, Colorado School of Public Health, University of Colorado, Anschutz Medical Campus, Aurora, CO, the United States of America.
Lyndsay KrisherCenters for Health, Work, & Environment, Colorado School of Public Health, University of Colorado, Anschutz Medical Campus, Aurora, CO, the United States of America; Department of Environmental and Occupational Health, Colorado School of Public Health, University of Colorado, Anschutz Medical Campus, Aurora, CO, the United States of America.
Karely Villarreal HernandezCenters for Health, Work, & Environment, Colorado School of Public Health, University of Colorado, Anschutz Medical Campus, Aurora, CO, the United States of America.
Laura CalvimontesDepartment of Environmental and Radiological Health Sciences, Colorado State University, Fort Collins, CO, the United States of America.
Grant ErlandsonDepartment of Environmental and Radiological Health Sciences, Colorado State University, Fort Collins, CO, the United States of America.
James SeidelDepartment of Environmental and Radiological Health Sciences, Colorado State University, Fort Collins, CO, the United States of America.
Colton CastroDepartment of Environmental and Radiological Health Sciences, Colorado State University, Fort Collins, CO, the United States of America.
Stephen BrindleyCenters for Health, Work, & Environment, Colorado School of Public Health, University of Colorado, Anschutz Medical Campus, Aurora, CO, the United States of America; Department of Environmental and Occupational Health, Colorado School of Public Health, University of Colorado, Anschutz Medical Campus, Aurora, CO, the United States of America.
Yaqiang LiCenters for Health, Work, & Environment, Colorado School of Public Health, University of Colorado, Anschutz Medical Campus, Aurora, CO, the United States of America; Department of Environmental and Occupational Health, Colorado School of Public Health, University of Colorado, Anschutz Medical Campus, Aurora, CO, the United States of America.
Miranda DallyCenters for Health, Work, & Environment, Colorado School of Public Health, University of Colorado, Anschutz Medical Campus, Aurora, CO, the United States of America; Department of Environmental and Occupational Health, Colorado School of Public Health, University of Colorado, Anschutz Medical Campus, Aurora, CO, the United States of America.
Katherine A JamesCenters for Health, Work, & Environment, Colorado School of Public Health, University of Colorado, Anschutz Medical Campus, Aurora, CO, the United States of America; Department of Environmental and Occupational Health, Colorado School of Public Health, University of Colorado, Anschutz Medical Campus, Aurora, CO, the United States of America; Department of Epidemiology, Colorado School of Public Health, University of Colorado, Anschutz Medical Campus, Aurora, CO, the United States of America.
Richard J JohnsonDivision of Renal Diseases and Hypertension, University of Colorado School of Medicine, Anschutz Medical Campus, Aurora, CO, the United States of America.
Daniel PilloniPantaleon, Guatemala City, Guatemala.
Alex CruzPantaleon, Guatemala City, Guatemala.
Nicholas SmithIndependent Researcher, Guatemala.
Evan JohnsonDivision of Kinesiology & Health, University of Wyoming, Laramie, WY, the United States of America.
Joshua W SchaefferDepartment of Environmental and Radiological Health Sciences, Colorado State University, Fort Collins, CO, the United States of America.
John L AdgateDepartment of Environmental and Occupational Health, Colorado School of Public Health, University of Colorado, Anschutz Medical Campus, Aurora, CO, the United States of America.
Lee S NewmanCenters for Health, Work, & Environment, Colorado School of Public Health, University of Colorado, Anschutz Medical Campus, Aurora, CO, the United States of America; Department of Environmental and Occupational Health, Colorado School of Public Health, University of Colorado, Anschutz Medical Campus, Aurora, CO, the United States of America; Department of Epidemiology, Colorado School of Public Health, University of Colorado, Anschutz Medical Campus, Aurora, CO, the United States of America; Division of Pulmonary Sciences and Critical Care Medicine, Department of Medicine, University of Colorado School of Medicine, Anschutz Medical Campus, Aurora, CO, the United States of America.

Funding

Particulate exposure and kidney health: Diversity Supplement Villarreal HernandezR01ES031585 · NIEHS · UNIVERSITY OF COLORADO DENVER · PI JOHN L. ADGATE, LEE S NEWMAN · 2021 to 2026
$3.9M
NIEHS NIH HHS R01 ES031585
6 · The paper itself

Abstract

backgroundRising global temperatures raise concerns about climate change's health impacts. Agricultural workers are particularly vulnerable due to prolonged exposure to heat and environmental pollutants, including airborne particulate matter (PM), which may increase their risk for kidney injury. This study explores the relationships between core body temperature (CBT), markers of hydration, PM exposure, and kidney injury, offering insights into public health risks related to climate change.

methodsWe conducted a longitudinal study of 148 sugarcane workers in Guatemala, monitoring them over 378 person-workdays. CBT and personal PM exposure were recorded throughout the workday, while markers of hydration and kidney function were assessed pre- and post-shift. Linear mixed-effects models were used to assess the relationships between these exposure factors, dehydration markers, and serum creatinine changes, an indicator of kidney injury.

findingsCBT exceeded 38.0 °C on 53 % of workdays, with 15 % surpassing 38.5 °C. Higher urinary specific gravity (β: 3.82, 95 % CI: 0.84, 6.80), serum uric acid (β: 2.46, 95 % CI: 0.70, 2.14), average heat index (β: 1.33, 95 % CI: 0.53, 2.14), and CBT exceeding 38.5 °C (β: 8.95, 95 % CI: 2.89, 15.02) were significantly associated with cross-shift increases in serum creatinine. Despite substantial PM

conclusionsHeat strain and dehydration are significant contributors to kidney injury in agricultural workers, highlighting critical public health risks. These findings emphasize the urgent need for interventions to mitigate heat-related health hazards, including workplace protections, hydration strategies, and climate adaptation policies to safeguard vulnerable populations worldwide.

Indexed as

Air PollutionHeat Stress DisordersHot TemperatureKidneyKidney DiseasesOccupational ExposureAdultCreatinineFarmersGuatemalaHumansLongitudinal StudiesMaleParticulate MatterWorking ConditionsCreatinineParticulate MatterClimate ChangeHeatKidneyParticulate MatterWorker

Identifiers

PMID41506105
PMCPMC13446998

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.