Evidence map›Paper›PMID 41505744›Full record

ArticleJMIR research protocols2026

Effects of Performing Eccentric Contractions to Failure After Concentric Muscle Failure in Resistance Training Sessions: Protocol for a Within-Participant Randomized Trial.

Pedro Henrique Alves Campos, Renan Vieira Barreto, Gabriel Fontanetti, Leonardo Santos Lopes da Silva, Matheus Machado Gomes, Leonardo Lima

Abstract readClinical Trial Protocol
In one paragraph

Article in JMIR research protocols, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Pedro Henrique Alves Campos *School of Physical Education and Sport of Ribeirão Preto, University of São Paulo, Ribeirão Preto, Brazil.ORCID 0009-0008-8113-3708
Renan Vieira Barreto *Department of Physical Education, Institute of Biosciences, São Paulo State University, Rio Claro, Brazil.ORCID 0000-0003-2734-4359
Gabriel Fontanetti *School of Physical Education and Sport of Ribeirão Preto, University of São Paulo, Ribeirão Preto, Brazil.ORCID 0000-0002-7506-7598
Leonardo Santos Lopes da Silva *School of Physical Education and Sport of Ribeirão Preto, University of São Paulo, Ribeirão Preto, Brazil.ORCID 0000-0001-7028-1352
Matheus Machado Gomes *School of Physical Education and Sport of Ribeirão Preto, University of São Paulo, Ribeirão Preto, Brazil.ORCID 0000-0002-2123-5699
Leonardo Lima *School of Physical Education and Sport of Ribeirão Preto, University of São Paulo, Ribeirão Preto, Brazil.ORCID 0000-0003-4118-534X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundResistance training is a well-established strategy to promote muscle hypertrophy and strength gains. Performing sets to concentric muscle failure (MF

objectiveThis study aims to investigate whether performing additional eccentric contractions to eccentric muscle failure (MF

methodsIn a randomized within-subject design, untrained young adult females will perform 2 upper-limb resistance training protocols over 10 weeks, including traditional (TRAD) training to MF

resultsAs of July 2024, a total of 7 participants have completed the intervention. Data collection was conducted between March and July 2024, with a new phase planned for the first half of 2025. Manuscript submission is expected in the second half of 2025.

conclusionsIf the hypothesis is confirmed, the ECC+ protocol may represent a practical, simple, and low-cost strategy to increase training volume and optimize strength and hypertrophy outcomes. This study may contribute to evidence-based resistance training prescriptions, particularly for women, and support the use of additional eccentric contractions as an effective tool to enhance localized muscle adaptations. INTERNATIONAL REGISTERED REPORT IDENTIFIER (IRRID): DERR1-10.2196/67537.

Indexed as

Muscle ContractionMuscle, SkeletalResistance TrainingAdaptation, PhysiologicalAdultFemaleHumansMuscle StrengthRandomized Controlled Trials as TopicYoung Adulteccentric exerciseexercise-induced muscle damagemuscle functionmuscle hypertrophyresistance training

Identifiers

PMID41505744
PMCPMC12828313

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.