Evidence map›Paper›PMID 41505661›Full record

ArticlePLoS medicine2026

Public health impacts of increasing the minimum unit price for alcohol in Scotland: A model-based appraisal.

John Holmes, Damon Morris, Duncan Gillespie, Alan Brennan, Grace Leeming, Ryan Kai Le Chen, Luke Wilson, Colin Angus

Abstract read
In one paragraph

Article in PLoS medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

John HolmesSheffield Addictions Research Group, Sheffield Centre for Health and Related Research, University of Sheffield, Sheffield, United Kingdom.ORCID https://orcid.org/0000-0001-9283-2151
Damon MorrisSheffield Addictions Research Group, Sheffield Centre for Health and Related Research, University of Sheffield, Sheffield, United Kingdom.ORCID https://orcid.org/0000-0001-6757-5333
Duncan GillespieSheffield Addictions Research Group, Sheffield Centre for Health and Related Research, University of Sheffield, Sheffield, United Kingdom.ORCID https://orcid.org/0000-0003-3450-5747
Alan BrennanSheffield Addictions Research Group, Sheffield Centre for Health and Related Research, University of Sheffield, Sheffield, United Kingdom.
Grace LeemingSheffield Addictions Research Group, Sheffield Centre for Health and Related Research, University of Sheffield, Sheffield, United Kingdom.ORCID https://orcid.org/0000-0003-4836-7840
Ryan Kai Le ChenSheffield Addictions Research Group, Sheffield Centre for Health and Related Research, University of Sheffield, Sheffield, United Kingdom.
Luke WilsonSheffield Addictions Research Group, Sheffield Centre for Health and Related Research, University of Sheffield, Sheffield, United Kingdom.ORCID https://orcid.org/0000-0001-5769-5729
Colin AngusSheffield Addictions Research Group, Sheffield Centre for Health and Related Research, University of Sheffield, Sheffield, United Kingdom.ORCID https://orcid.org/0000-0003-0529-4135

Funding

Wellcome Trust
6 · The paper itself

Abstract

backgroundGovernments in several countries have introduced a minimum unit price (MUP) for alcohol. Evaluation studies suggest this has reduced alcohol-related harm, but MUPs must increase with inflation to remain effective. This paper estimates the impact of the impact of the Scottish Government's decision to increase its MUP from £0.50 to £0.65 in September 2024 and, alternative options where the MUP changes to between £0.40 and £0.80. It examines impacts on alcohol consumption, spending, and related health outcomes, how impacts vary across the population with regard to deprivation, and how drinkers move between lighter and heavier alcohol consumption groups. METHODS AND

findingsPolicy appraisal using the Sheffield Tobacco and Alcohol Policy Model, a dynamic microsimulation model that combines data on alcohol purchasing and consumption for 10 beverage types and 800 subgroups comprising adults in the Scottish population with price elasticities and an epidemiological model. Deprivation is measured using quintiles of the Scottish Index of Multiple Deprivation. Drinker group is categorised as moderate (<14 units/week, 1 UK unit = 8 g ethanol), hazardous (>14 to ≤35/ ≤50 units/week for women/men), and harmful (>35/50 units/week for women/men). The policy appraisal estimates that, compared to retaining Scotland's MUP at £0.50, increasing the MUP to £0.65 leads to an estimated 12.0% decrease in alcohol consumption, 2.1% decrease in alcohol spending, 3,385 fewer deaths overall, and 2,578 fewer deaths wholly attributable to alcohol over 20 years. Estimated effects are largest in the quintile of the population living in the most deprived areas. Increasing the MUP to £0.65 is also estimated to reduce the proportion of drinkers consuming at harmful levels by 29.4% and the proportion consuming at hazardous levels by 8.0%. Key limitations of the study include relying on data on alcohol consumption and spending collected before the COVID-19 pandemic, synthesising consumption and spending data from separate datasets, and assuming no supply-side responses (e.g., price changes above the MUP threshold).

conclusionsIncreasing the threshold of an established MUP can lead to additional reductions in alcohol consumption, related harm, and health inequalities. Benefits accrue particularly to the most deprived and heaviest drinkers.

Indexed as

Alcohol DrinkingAlcoholic BeveragesCommercePublic HealthAdultFemaleHealth PolicyHumansMaleScotland

Identifiers

PMID41505661
PMCPMC12782643

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.